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Preventing exhaustion in immune cells boosts immunotherapy in mice
Research shows that preventing or reversing ‘T-cell exhaustion’ with targeted therapies could enhance the effects of immunotherapy.
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Stem Cells
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Six leading pharma firms to participate at Pharmaceutical Microbiology event in San Diego
SMi’s 2nd Annual Pharmaceutical Microbiology West Coast Conference will be taking place in San Diego, USA on the 7th - 8th June 2018.
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Scientists identify new stem cell that helps regenerate lung tissue after trauma
Researchers from the University of Pennsylvania have identified a lung stem cell that repairs the organ's gas exchange compartment, providing potential new approach to treat lung disease.
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Pancreatic stem cells have potential to regenerate beta cells
Findings pave way for regenerative cell therapies in type 1 diabetes patients...
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Neural stem cell treatment may offer relief for MS
Scientists have shown that skin cells re-programmed into brain stem cells, transplanted into the central nervous system, help reduce inflammation and may be able to help repair damage caused by MS...
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Microengineered intestinal lining mirrors living tissue inside organ-chip
Microengineered Intestine-Chip has the potential to advance personalised treatments for gastrointestinal diseases...
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iPS cells could serve as an effective cancer vaccine
A study in mice has suggested that iPS cells may train the immune system to attack or even prevent tumours...
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Small molecule could make a big difference for arthritis patients
Scientists have discovered a molecule that enhances cartilage regeneration and decreases inflammation.
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PGEC-derived organoids produce stable gut and liver tissue
Researchers have bioengineered organs that are free from the risk of tumour growth--and of sufficient volume and size for viable transplant...
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Scientists target glioma cancer stem cells which could improve patient survival
Dartmouth scientists have successfully uncovered a therapeutic approach that targets aggressive brain cancer stem cells and could lead to improved patient survival.
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Operetta CLS High-Content Analysis System
6 February 2018 | By PerkinElmer
Operetta CLS is a high-content cell analysis system featuring a unique combination of technologies to deliver high speed, sensitivity, and resolution...
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Reprogrammed brain cells exhibit symptoms of Huntington’s disease
Scientists have transformed skin cells from patients with Huntington's disease into the type of brain cell affected by the disorder...
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New to 2018: The role of artificial intelligence in drug discovery
SMi Reports: SMi’s 2nd annual Drug Discovery conference, taking place in London on 21 and 22 March 2018, will discuss the role of artificial intelligence in drug discovery.
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Uncovering the early origins of Huntington’s disease using CRISPR engineered embryonic stem cells
Researchers have developed a system to model Huntington's in human embryonic stem cells...
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ZNF274 deletion reverses Prader-Willi syndrome
Reversing the imprinting that causes Prader-Willi syndrome gives hope that epigenetic diseases can be cured...
