NGLY1 protein identified as potential target for melanoma treatment
Scientists in the United States have inadvertently uncovered a promising treatment for melanoma that targets the NGLY1 gene.
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Tethered antibodies may prevent influenza virus infections
Investigational therapeutic candidate made with four antibodies tethered together shows promise against influenza A and B...
Stem cell therapy with biodegradable scaffold
A biodegradable scaffold used to transplant stem cells and deliver drugs, could help in the treatment of brain diseases...
Heat-resistant enzymes for cost-effective drugs
The mechanisms and actions of heat-resistant enzymes are being investigated to aid better, more cost-effective drug design...
Charles River to present collaborative methods at Neuroscience 2018
Charles River Laboratories International, Inc. (NYSE: CRL) announced that its team of neuroscience drug discovery experts will present 26 scientific posters, both independently and collaboratively with clients, at Neuroscience 2018, the 48th annual meeting of the Society for Neuroscience (SfN)...
Charles River and Distributed Bio enter exclusive partnership to create an integrated antibody discovery and development platform
Charles River Laboratories International, Inc. announced that it has entered into an exclusive partnership with Distributed Bio, Inc., a leader in the computational design and optimisation of antibody discovery platforms...
Biomarkers may predict Zika-related birth defects
Researchers have identified biomarkers associated with severe birth defects in babies born to women infected with the Zika virus...
Image of serotonin activating its receptor for the first time
Researchers have managed to image serotonin activating its receptor for the first time using the cutting edge technology, cryo-electron microscopy...
MDM2 inhibitors as a possible treatment for uveitis
MDM2 inhibitors could be used as a treatment for uveitis, a disease affecting the middle layer of the eye, causing inflammation and redness...
New Cas9 enzyme widens scope for CRISPR genome editing
A team of researchers has discovered a Cas9 enzyme that can target almost half of the locations on the genome, significantly widening its potential application.
Antibacterial compounds focusing on LsrK kinase
Researchers at the University of Eastern Finland have developed antibacterial compounds based on the action of LsrK kinase...
Biomarker discovered for heart failure with preserved ejection fraction
A biomarker has been discovered for the most common type of heart failure - heart failure with preserved ejection fraction...
Skeletal stem cells de-differentiate to achieve extensive growth
Researchers in the U.S. have discovered that skeletal stem cells in the jaws of adult mice de-differentiate when tasked with regenerating large portions of bone and tissue.
Biomarkers to detect and prevent liver cancer
An increase in the expression of sugar-burning 'glycolytic' enzymes in precancerous cirrhotic livers has been identified and could be used as a biomarker...
Droplet Digital PCR detects and quantifies cancer mutation
Two ddPCR-based assays were developed to detect the two mutations in the promoter region of the TERT gene, which could be used as biomarkers...
