Progress toward improved Wilson’s disease drug
Researchers have conducted promising preclinical experiments on a compound that could be used to treat Wilson's disease...
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Scientists uncover the mechanism by which cancer cells resist ageing
Scientists in the U.S. have found that human lung cancer cells resist dying by controlling parts of the ageing process. The discovery could help us better understand ageing and eventually lead to new treatments for cancer.
Experimental drug combined with radiation extends the survival of GBM
A new study has shown that an experimental drug known as AZ32 significantly extends the survival of glioblastoma multiforme, the most common and deadly form of brain cancer...
Nuclear medicine technique to gauge impact of gene therapy
A new molecular imaging method can monitor the success of gene therapy in all areas of the brain, potentially allowing physicians to more effectively address brain conditions such as Parkinson's disease, Alzheimer's disease and multiple sclerosis.
Researchers report success culturing Treponema pallidum, which causes syphilis
Researchers have described a new method for culturing Treponema pallidum, that until now it couldn't be cultured in a lab dish...
CLR01 protein found in semen increases the spread of Ebola virus infection
Penn study suggests that targeting amyloid fibrils could prevent sexual transmission...
Genes linking Alzheimer’s and Down syndrome discovered
Scientists are a step closer to understanding which genes are responsible for early-onset Alzheimer's disease in people with Down syndrome...
CRISPR-Gold used to reduce repetitive behaviours in FXS
Gold nanoparticles carried Cas9 enzyme into brain, editing receptor and lessening burying behaviour...
Researchers reveal therapeutic target for Influenza A
Researchers show altering the molecular interactions between the flu virus and host genes stunts virus replication...
NIH-funded study finds new evidence that viruses may play a role in Alzheimer’s disease
Analysis of large data sets from post-mortem brain samples of people with and without Alzheimer's disease has revealed new evidence that viral species, particularly herpesviruses, may have a role in Alzheimer’s disease biology.
Bioactivity profiling supporting the progression of phenotypic hits
Addressing the optimisation of hits derived from a target-agnostic phenotypic screen, using a strategy based on combining bioactivity profiling and reference compound characterisation...
Researchers uncover new target to stop cancer growth
Researchers have discovered that a protein called Munc13-4 helps cancer cells secrete large numbers of exosomes that stimulate tumour progression...
Human immune ‘trigger’ map paves way for better treatments
A discovery about how human cells are 'triggered' to undergo an inflammatory type of cell death could have implications for treating cancer, stroke and tissue injury, and immune disorders...
Molecular alterations provide insight into Huntington’s disease
Scientists have applied their high-throughput, multi-pronged approach to Huntington's disease, and uncovered the functional significance of various molecular changes...
ATP1A3 gene mutations associated with infantile forms of schizophrenia
Scientists have identified novel genes associated with a specific form of schizophrenia the discovery will aid diagnosis and development of treatments...
