Scientists discover why moles stop growing
6 August 2015 | By Victoria White
Researchers from the University of Pennsylvania have identified a major genetic factor that keeps moles in their usual non-cancerous, no-growth state...
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MedImmune and Mirati in lung cancer therapy collaboration
6 August 2015 | By Victoria White
MedImmune has entered into an exclusive clinical trial collaboration with Mirati Therapeutics to evaluate durvalumab in combination with mocetinostat...
AstraZeneca and Heptares to develop novel immuno-oncology treatments
6 August 2015 | By Victoria White
AstraZeneca and Heptares Therapeutics have entered into a licensing agreement to develop A2A receptor-blocking compounds as cancer immunotherapies...
ADXS-PSA awarded grants from PCF and Movember Foundation
5 August 2015 | By Victoria White
Two research projects involving ADXS-PSA, which is being developed for prostate cancer, have been selected for 2015 Movember Foundation-PCF Challenge Awards...
Pharmaxis and Synairgen team up to develop LOXL2 inhibitor
5 August 2015 | By Victoria White
Pharmaxis and Synairgen are to collaborate to develop a selective inhibitor to the LOXL2 enzyme to treat idiopathic pulmonary fibrosis...
MorphoSys and G7 Therapeutics to develop antibodies targeting GPCRs
4 August 2015 | By Victoria White
MorphoSys and G7 Therapeutics have signed an agreement to collaborate on novel antibody therapeutics targeting G protein-coupled receptors (GPCRs)...
Oncology treatment pipeline offers significant opportunities
4 August 2015 | By Victoria White
The oncology drug pipeline is far larger than any other therapy area with 6,484 products in active development across all indications...
Nanoparticles used to breach lung mucus barrier
4 August 2015 | By Victoria White
Researchers have used nanoparticles to breach the human airway mucus barrier of lung tissue - a finding that could lead to effective drug delivery systems...
Global vaccine-development fund could save thousands of lives
4 August 2015 | By Victoria White
For vaccine development, financial barriers persist: pharma companies see high costs with limited market potential, and government support is lacking...
Neuroblastoma cells drain immune system’s batteries
3 August 2015 | By Victoria White
Cancer cells in neuroblastoma contain a molecule that breaks down a key energy source for immune cells, leaving them too drained to fight the disease...
Prokarium gets funding from SynbiCITE to develop chlamydia vaccine
3 August 2015 | By Victoria White
Prokarium has received new funding from SynbiCITE that will enable it to complete preclinical development of an innovative chlamydia vaccine...
AZ and Isis Pharmaceuticals to discover antisense drugs
3 August 2015 | By Victoria White
AstraZeneca and Isis Pharmaceuticals are to collaborate to discover and develop antisense therapies for cardiovascular, metabolic and renal diseases...
Oxford Global’s Q&A session with Drug Discovery USA speaker Matthew Wagoner, a discovery safety specialist from AstraZeneca
31 July 2015 | By Oxford Global
In the run up to our 2nd Annual Drug Discovery USA Congress 2015, we spoke with Matthew Wagoner a discovery safety specialist from AstraZeneca, a confirmed speaker at the congress where he will talk about Bromodomain And ExtraTerminal (BET) Domain Inhibitors Induce A Loss Of Intestinal Stem Cells And Villous…
St Jude scientists identify new mechanism of p53-induced cell death
31 July 2015 | By Victoria White
Researchers have identified a new mechanism that the tumour suppressor protein p53 uses to trigger cell death via apoptosis...
Researchers resurrect ancient virus to improve gene therapy
31 July 2015 | By Victoria White
Researchers have reconstructed an ancient virus that is highly effective at delivering gene therapies to the liver, muscle, and retina...