whitepaper
Application note: Effect of perfluorinated alcohols in impurity analysis for synthetic oligonucleotides
Therapeutic oligonucleotides represent a recent breakthrough in the pharmaceutical industry.
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Analytical Techniques
whitepaper
Application note: Effect of alkylamine based Ion-pairing reagents in analysis of siRNA
Silencing RNA, or siRNA, are short, double-stranded RNA molecules which are not only an important research tool in molecular biology, but also an emerging therapeutic modality.
whitepaper
Application note: Comparison of fully porous and superficially porous particles for the analysis of synthetic oligonucleotides
Superficially porous particle technologies provide a reduced diffusion path in comparison with their fully porous counterparts minimising the resistance to mass transfer during chromatographic separation.
article
Revealing the genetic signature of neurodegenerative disease
Which immune cells contribute towards immune-induced neurodegeneration and how could this knowledge enable conditions such Alzheimer’s and multiple sclerosis to be treated?
news
Could the Nsp1 protein be a novel drug target for COVID-19?
A study of the SARS-CoV-2 nonstructural protein 1 (Nsp1) showed it can supress translation and inhibit anti-viral defence mechanisms, making it a potential target for drugs.
news
Complete DNA sequence of the X chromosome revealed
Researchers capitalised on novel sequencing technologies to produce the first end-to-end DNA sequence of the X chromosome.
video
On-demand webinar: How to be a spectral superstar – NMR & MS analysis made easy
Software to help synthetic and medicinal chemists process and analyse all their spectral data in a single location.
webinar
Mobile phase optimisation for oligonucleotide analytical methods by LC-MS
1 July 2020 | By Phenomenex
In this on-demand webinar, we provide an overview of nucleic acid therapeutics and discuss the chromatographic challenges associated with oligonucleotides. We also explore modulation of the mobile phase additives alkylamine ion pair and perfluorinated alcohols. Finally, we will show how optimisation of mobile phase can improve not only chromatographic performance…
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Case study: Takeda streamline analytical handling
Read how Takeda simplified analytical data processing for their Process and Medicinal chemists by consolidating to a single piece of software.
whitepaper
Case study: Better, faster method development at Janssen
Learn how method development software helped Janssen Pharmaceuticals reduce method development time by 80% with a 25-fold increase in method quality
webinar
Drug repurposing approaches to fast track development of new therapies for COVID-19
26 June 2020 | By Tecan
This webinar described the recent efforts to identify small molecule therapeutics for the treatment of SARS-CoV-2 infection and COVID-19 disease.
whitepaper
ebook: The researcher’s guide to measuring binding affinity
Learn why measuring binding affinity is key to helping you decide the next steps in your research and what technologies are available to measure it.
whitepaper
ebook: The definitive guide to understanding protein stability
Learn how to measure protein stability, why it’s important, and what the key technologies are available to measure it.
video
Video: ESHG 2019 conference discussion panel: automated sample preparation
A result is only as good as the sample preparation that preceded it.
video
Video: Overview of the KingFisherTM instruments
ESHG 2019: Automated sample preparation using magnetic bead technology and KingFisher instruments.
