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3D image of insulin and its receptor revealed
After combining over 700,000 2D images, researchers have finally been able to build a 3D image of how insulin binds to its receptor...
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Disease Research
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Scientists image antibodies working together against malaria
Cryo-EM was used to image the antibodies attaching to the circumsporozoite protein, which is the most abundant protein on the surface of malaria...
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Helping blood cells to regenerate after radiation therapy
Researchers at MIT have identified a way to stimulate a particular stem cell in order the hasten the regeneration of red blood cells...
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Protein sequencing method could transform biological research
A team of researchers have demonstrated a new way to sequence proteins that are much more sensitive than existing technology, identifying individual protein molecules rather than requiring millions of molecules at a time
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Protein adhesion complex cell structure identified
A cell structure identified has given an insight into how cells attach to their surroundings, and could be used to discover potential actions of new drugs...
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Antiphospholipid antibodies linked to heart attacks
Levels of antiphospholipid antibodies, which are associated with rheumatic diseases, are also elevated in myocardial infarction without any autoimmune co-morbidity...
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Single molecule fluorosequencing to transform biological research
Single molecule fluorosequencing could revolutionise the way researchers analyse disease, with the method enabling the investigation of single cells...
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Critical cancer immunity genes identified using genetic barcoding
Genetic barcoding using Pro-codes and CRISPR could be used to identify critical cancer immunity genes to aid future therapeutics...
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Protein mTOR regulated by Src in cancer growth
Researchers at Baylor College of Medicine and Texas Children's Hospital have identified a connection between cancer proteins mTORC1 and Src...
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Better drug delivery through the blood-brain barrier
Drug delivery through the blood-brain barrier has shown to be difficult to overcome, but researchers may have discovered a method to overcome this issue...
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Novel DNA vaccine offers broad protection against Influenza-A H3N
Researchers developed a novel DNA influenza vaccine based on four micro-consensus antigenic regions selected to represent the diversity of seasonal H3N2 viruses...
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Investigating tumour microenvironments for more effective treatments
Tumour microenvironments give insights into more effective therapies against lung cancer, a bigger killer than colon, prostrate and breast cancers combined...
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Key genomic differences in breast cancers of women of different ethnicity
Study of genomic data from breast cancers of Nigerian women, compared with American women, highlights significant differences that may help targeted treatment for the epidemic across Sub-Saharan Africa.
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Immunotherapy targeting blood protein fibrin
Targeting the fibrin protein could ensure that fibrin leaking through the blood-brain barrier does not cause inflammation or disease in the brain...
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miR-31 may help target treatments for Crohn’s patients
Researchers have pinpointed a single molecule - microRNA-31 (miR-31) - the levels of which predict whether a patient has subtype 1 or subtype 2 of Crohn's disease...
