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Drug Development

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Charles River announces expansion of in vitro oncology services

30 October 2017 | By Charles River Laboratories

Partnership with InSphero provides additional 3D solutions...

news

Self-regulating nanoparticles could treat cancer

24 October 2017 | By Dr Zara Kassam (Drug Target Review)

Scientists have developed 'intelligent' nanoparticles which heat up to a temperature high enough to kill cancerous cells...

news

Inhibiting β-lactamase may reverse antibiotic resistance

23 October 2017 | By Dr Zara Kassam (Drug Target Review)

By developing a chemical to inhibit β-lactamase enzymes, a significant proportion of antibiotic resistance may successfully be reversed...

news

DNA-based Zika vaccine found effective at inducing immune response

5 October 2017 | By Dr Zara Kassam (Drug Target Review)

A new generation DNA-based Zika vaccine is the first to demonstrate both safety and the ability to elicit an immune response against Zika in humans...

news

Novartis and UC Berkeley collaborate to tackle ‘undruggable’ disease targets

28 September 2017 | By Dr Zara Kassam (Drug Target Review)

Collaboration aims to unlock difficult drug targets and accelerate the discovery of new medicines in areas such as infectious diseases and cancer...

news

Streamlined process opens drug development to a new class of steroids

26 September 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have developed a technique to produce synthetic steroids that could pave the way for a cascade of new drug discoveries...

news

Bryostatin-1 shows early promise for dormant HIV infection

22 September 2017 | By Dr Zara Kassam (Drug Target Review)

Scientists have designed a synthetic molecule bryostatin-1 that can reactivate dormant HIV...

news

A genetic approach to high insulin levels

18 September 2017 | By Dr Zara Kassam (Drug Target Review)

A team of researchers have succeeded in precisely describing the effects of a frequent genetic mutation in cases of congenital hyperinsulinism...

news

KDM4 inhibitor brings new hope for breast cancer

15 September 2017 | By Dr Zara Kassam (Drug Target Review)

Scientists have shown that inhibiting the epigenetic regulator KDM4 may offer a potential novel treatment for breast cancer...

news

NIH awards $15m to support development of 3-D human tissue models

13 September 2017 | By Dr Zara Kassam (Drug Target Review)

The NIH has announced 13 two-year awards totalling $15m, to develop 3-D microphysiological system platforms that model human disease...

news

DNA sequencing could open up new drug indications for rare cancers

8 September 2017 | By Dr Zara Kassam (Drug Target Review)

A network of hospitals have systematically collected biopsies from metastatic cancer patients in order to create a global database...

news

New mindset in the search for stroke therapies

7 September 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have identified a promising new avenue to explore in the search for stroke treatments...

news

Drug may curb female infertility from cancer treatments

4 September 2017 | By Dr Zara Kassam (Drug Target Review)

An existing drug may protect premenopausal women from life-altering infertility that commonly follows cancer treatments...

news

Chemo-boosting drug discovered for leukaemia

4 September 2017 | By Dr Zara Kassam (Drug Target Review)

Drugs developed to treat heart and blood vessel problems could be used to treat leukaemia...

news

Cell culture system could offer cancer breakthrough

31 August 2017 | By Dr Zara Kassam (Drug Target Review)

A new cell culture system that provides a tool for preclinical cancer drug development and screening has been developed...

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Drug Development