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New biomarker shows promise for pitch-side brain injury test
Researchers at the University of Birmingham have identified inflammatory biomarkers which indicate whether the brain has suffered injury.
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Drug Discovery
In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which new candidate medications are discovered.
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£2m grant for University collaboration antibiotic resistance study
Dr Reda Lebcir from the University of Hertfordshire is part of an international team of researchers awarded a £2m grant from the ESRC (Economic and Social research Council).
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New study reveals new drug target for gout & inflammatory diseases
Research reveals cathepsins as potential therapeutic targets in particulate-mediated inflammatory disease…
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Solution to accelerate drug discovery process by DDI analysis
Elsevier has launched a new solution aimed at accelerating drug discovery through comprehensive prediction and assessment of drug-drug interactions (DDI).
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Q&A: The role of disease focused foundations in bridging the drug discovery and development gap
Bio 2017 opens this week and Drug Target Review’s Niamh Marriott spoke with Richard Soll, Senior Vice President, Research Service Division, WuXi AppTec and Salvatore La Rosa, Vice President Research and Development, Children’s Tumor Foundation, to get their perspectives on one of the event’s most pressing trends. Both will be…
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Numab and Kaken enter into an antibody collaboration
Numab Therapeutics announced a collaboration and option agreement with Kaken Pharmaceutical for the identification of a multispecific antibody candidate for development in inflammatory disease.
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Eisai and Charles River Laboratories announce extension of integrated drug discovery partnership
Companies to continue collaboration in discovery of next generation anti-malaria drugs...
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Diabetes drug prevents cardiovascular disease in obese mouse study
A study by researchers at the University of Missouri School of Medicine found that the diabetes medication linagliptin can protect against stiffening of the left ventricle of the heart in overweight female mice. The finding may have implications for management of cardiovascular disease in humans.
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Screening In-Depth Focus 2017
Included in this Screening In-Depth Focus: Phenotypic and target-based screening; Killing cancer cells using clinical drug resistance; Inflammatory biomarkers as a herbal anti-arthritic drug discovery tool...
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Drug Target Review – Issue #2 2017
Included in this issue: Technology convergence improves testing; Screening; Stem Cells; Targets; Mass Spectrometry; and Therapeutics in Alzheimer's disease...
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The immune system promotes spontaneous heart regeneration
In adult mammal hearts, cardiomyoctyes do not proliferate following damage, like that caused by myocardial infarction.
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Optibrium, Imperial College and DNDi to collaborate on drug development
The collaboration will provide MSc students with industry-relevant learning tools and pharma with a new pipeline of candidate compounds.
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Making biological drugs with spider silk protein
Researchers at the Karolinska Institutet in Sweden have managed to synthesise lung surfactant, a drug used in the care of preterm babies, by mimicking the production of spider silk.
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Scientists to test Zika virus on brain tumours
The research, using tumour cells in the laboratory and in mice, will see if the Zika virus can destroy cancer cells.
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Preclinical candidate CGRP antagonist has potential as treatment for migraines
A preclinical candidate calcitonin gene-related peptide (CGRP) antagonist has been nominated for advancement into further preclinical studies as an investigational treatment for migraine.
