news
Charles River Laboratories acquires Agilux Laboratories, Inc.
13 October 2016 | By Charles River Laboratories
Enhances Charles River’s early-stage capabilities in bioanalytical services...
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Drug Discovery
In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which new candidate medications are discovered.
whitepaper
Whitepaper: Uncover specific correlations in heterogeneous cell populations during drug development
Integrating the S3e™ Cell Sorter into sample preparation upstream of the QX200™ Droplet Digital System provided details about cell subpopulations that would have been undetectable in heterogeneous populations...
news
Charles River Laboratories and The Tri-Insitutional Therapeutics Discovery Institute announce strategic partnership
26 September 2016 | By Charles River Laboratories
Partnership intends to accelerate translation of discoveries into novel therapies for patients...
article
A picture is worth a thousand endpoints: high-content imaging in drug discovery
Over the past few years several factors in the drug discovery industry have come together to drive an increased interest and subsequent surge in the use of high-content imaging. These include the high costs of attrition in the clinic due to lack of efficacy; increased hurdles and rising costs to…
article
Hit-to-lead in drug discovery
Starting in the 1970s, the drug discovery research process changed dramatically. Our understanding of biological targets and pathways grew and the largely empirical and target agnostic in vivo pharmacology approach was replaced with target-centric methods...
news
Charles River Laboratories announces partnership with the Milner Therapeutics Institute and Consortium
10 August 2016 | By Charles River Laboratories
Charles River Laboratories announced that it has entered into a strategic partnership with the Milner Therapeutics Institute and Consortium...
product
Bio-Rad CFX96 Touch™ Real-Time PCR Detection System
4 August 2016 | By Bio-Rad Laboratories
The CFX96™ Optical Reaction Module converts the C1000 Touch™ Thermal Cycler chassis into the powerful and precise CFX96 Touch Real-Time PCR Detection System...
article
Translating stem cell biology into drug discovery
Pluripotent stem cell research has made extraordinary progress over the past decade. The robustness of nuclear reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) has created entirely novel opportunities for drug discovery and personalised regenerative medicine...
news
Tri-I TDI expands focus to include antibody drug discovery
17 June 2016 | By Victoria White, Digital Content Producer
Tri-I TDI will extend its current relationship with Takeda from the realm of small molecule discovery into the new research area of antibody drug discovery...
news
A powerful new method for finding drug candidates
15 June 2016 | By Victoria White, Digital Content Producer
Scientists from The Scripps Research Institute have developed a powerful new method for finding drug candidates that bind to specific proteins...
news
Prospective biobank studies can help improve drug development
15 June 2016 | By Victoria White, Digital Content Producer
According to a study, genetic research in large-scale prospective biobank studies can significantly improve the drug development pipeline and reduce costs...
news
GBI Research identifies first-in-class as panacea for pharma companies
14 June 2016 | By Mandy Parrett, Editorial Assistant
In the face of the enormous costs involved in bringing a drug to market, pharmaceutical companies are increasingly aiming to develop first-in-class treatments to maximise return on this heavy burden, notes intelligence provider, GBI Research.
article
Mechanism-informed phenotypic screening – the missing link for cancer drug discovery?
Cancer cells exhibit huge phenotypic diversity, with many well-defined phenotypes, such as invasion, deregulated proliferation and immune evasion, contributing to disease outcomes, making them uniquely amenable to phenotypic screening1...
news
LDC and McGill enter translational drug discovery partnership
7 June 2016 | By Victoria White, Digital Content Producer
LDC and McGill University are to work together to identify tools to help develop novel endoplasmic reticulum related diseases therapies...
news
AstraZeneca’s genomics initiative to transform drug discovery
22 April 2016 | By Victoria White, Digital Content Producer
AstraZeneca has launched an integrated genomics initiative to transform drug discovery and development across its entire research and development pipeline...
