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Mucus could be key to treating colon and airway diseases
The action of proteins that control mucus production could suggest clues to treating colon and airway conditions such as asthma or Crohn's disease...
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Drug Targets
A drug target is anything within a living organism to which a drug is directed and/or binds, resulting in a change in its behaviour or function.
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The path of metallodrugs in breast cancer cells
The path a metallodrug uses to target and kill cancer cells could be used to design drugs to target triple-negative breast cancer...
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Clusterin linked to both cardiac and metabolic diseases
The protein clusterin has been linked to different cardiometabolic syndrome risks, with researchers asking whether it could be a therapeutic target...
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Engineered dl355 virus has the potential to be an effective anticancer treatment
An engineered virus kills cancer cells more effectively than another virus currently used in treatments, according to Hokkaido University researchers...
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Drug compound could be next-generation treatment for aggressive form of AML
Researchers have developed a series of compounds that work not only on AML with common FLT3 mutation but also drug-resistant AML...
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New drug targets for BRCA-driven cancer uncovered
Preclinical study yields previously unreported, potent and generalisable hits representing potential drug targets for hereditary breast, ovarian cancer...
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DNA anticancer vaccine targets tumour neoantigens
A DNA vaccine developed through the use of unique tumour antigens could lead the way towards vaccinating people against cancer...
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Catching lung cancer early using molecular profiling
Researchers have identified how they can differentiate between lesions in the airways that are benign and those that could become cancerous...
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Gene responsible for prostate cancer spread identified
Identified using a computer algorithm, the NSD2 gene may be responsible for advancing the spread of prostate cancer, and so could be used as a drug target...
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‘Hidden pocket’ could be targeted to treat strokes
Researchers have identified a tiny hidden pocket on the NMDA receptor that could be targeted to treat strokes and seizures...
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How gut bacteria affect the treatment of Parkinson’s disease
Researchers have investigated the ability of gut microbiota to influence the bioavailability of levodopa, a drug used in the treatment of Parkinson's...
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ADM-RAMP2 system could be therapeutic target for retinal vein occlusion
Researchers suggest that the retinoprotectivity of the ADM-RAMP2 system makes it an ideal therapeutic target for central retinal vein occlusion (CRVO)...
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GREB1 gene potential drug target for prostate cancer treatment
Researchers in the US have discovered how a gene involved in regulating hormone receptors, GREB1, may contribute to drug resistance in some prostate cancer patients.
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Potential therapeutic target for ALS revealed
Strathmin2 could be used as a biomarker for amyotrophic lateral sclerosis (ALS), a debilitating condition with no proper diagnostic tests or treatments...
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CRISPR/Cas9 shown to limit impact of certain parasitic diseases
Researchers successfully used CRISPR/Cas9 to limit the impact of schistosomiasis and liver fluke infection...
