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A drug target is anything within a living organism to which a drug is directed and/or binds, resulting in a change in its behaviour or function.
Designing new drug molecules is crucial to R&D. Dr Sam Genway suggests that one way to improve and speed up this process is using AI inspired by language translation.
A study has discovered a molecule key in neuronal growth that could be used as a drug target to treat anxiety-related diseases.
A research team has developed a method for regenerating old brain stem cells from rat models, which could be used to treat age-related brain diseases.
Researchers have discovered that removing the enzyme, PHLPP1, improves outcomes in a mouse model of sepsis so could be a potential drug target.
Researchers have discovered the mechanism behind the spread of Leishmania, indicating a potential drug target.
New findings show that the environment for pancreatic cancers plays a role in its metastasis, revealing a new potential drug target.
A new study has revealed that glioblastomas contain four different types of cell which the researchers say should be treated separately.
Imaging methods are used by scientists to identify therapeutic targets and improve drug efficacy. This article lists five of the latest developments for imaging techniques.
Using a compound called PTC596 in combination with other drugs, researchers effectively treated pancreatic cancer in mice.
A study has found that signals from interferons can be blocked, allowing the immune system to attack tumours which provides a potential target.
Researchers have discovered a subtype of immune cells that contribute to allergic reactions and anaphylaxis, providing a drug target.
Researchers have identified the process behind cancer cell energy production, providing a drug target for treatments to inhibit growth.
New study shows that a subset of follicular helper T cells contributes to the hyposialylation of autoantibodies in rheumatoid arthritis.
Researchers have discovered the mechanism behind a gateway into cells for glutamine, illuminating potential ways to prevent cancer cells from getting nutrients.
A study has discovered that reducing expression of a key gene in neuroblastoma tumourigenesis is an important drug target for the condition.
