Screening identifies gene which protects cells from Zika virus
Researchers used screening to discover genes that protect the body against the Zika virus, which could inform potential therapies against the virus.
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A drug target is anything within a living organism to which a drug is directed and/or binds, resulting in a change in its behaviour or function.
Researchers used screening to discover genes that protect the body against the Zika virus, which could inform potential therapies against the virus.
Researchers have identified a key process behind senescence, or why cells age, which could be used to improve treatments for cancer.
Scientists have created the first completely artificial protein switch that can be ‘programmed’ to modify gene expression.
Researchers have developed a new HIV vaccine which has shown success in monkeys in pre-clinical trial studies.
Researchers have found that fat cells transfer cytokines to melanoma cells, which transforms them into aggressive tumours, indicating a drug target for the condition.
A new study has found a novel way to target an enzyme involved in cancer growth, which could inform therapeutics for the condition.
Researchers have identified a protein that plays a role in promoting blood cancer and have successfully used a novel compound to inhibit it, reducing tumour growth.
Researchers have found a set of genes which helps cells survive during sepsis in mice and could inform potential treatments for the condition.
An antibody has been developed to block a protein secreted by the cells surrounding ovarian and pancreatic cancer tumours.
CD4+ T-cells play a central role in directing adaptive immune responses against invading microbial pathogens.
Immune cell isolation and culture are necessary for both basic research aimed at investigating the functions of different immune cell types, and for expanding specific immune cell populations for therapeutic purposes.
In figures released by the Home Office, the use of animal models has decreased down to 3.52 million procedures in 2018.
A study has discovered that the damage of projection neurons in the brain is caused by immune cells, leading to MS.
A protein has been discovered as key for effective chemotherapy, meaning improved treatments for chemotherapy resistance can be developed.
A study has identified a gene key in the spread of cancer, which could point to improving treatments for the condition, say the researchers.