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Gene activity app could reduce live model usage
Researchers have developed an app which displays the effects of diseases in mice models and can be accessed globally.
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Drug Targets
A drug target is anything within a living organism to which a drug is directed and/or binds, resulting in a change in its behaviour or function.
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Study reveals antioxidant role in spread of lung cancer
Researchers have discovered that lung cancer cells metastasise using antioxidants, informing potential future therapies.
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Study suggests immune cells play vital role in fungal disease
New research has revealed the immune cells may be critical in moving pathogenic fungal spores to the central nervous system, pointing to drug target.
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First patient enrolled in Parkinson’s treatment study
A trial has begun in the US for the ENT-01 therapy treatment of Parkinson’s, with the first patient enrolled.
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Novel technique reveals how TB antibiotics reach their targets
Researchers have used a new method to understand how antibiotics fight TB, which can guide future drug developments.
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Betaine supplement reduces schizophrenic behaviours in mice
A new study found that betaine supplementations given to mice reduced schizophrenic behaviours, indicating a drug target.
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Boosting immune cells could provide TB treatment
A new study has identified a class of immune cells that respond to tuberculosis, indicating a drug target for the condition.
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Potential drug target for Alzheimer’s identified
New research has identified an enzyme which causes degradation of dendritic spines, pointing to a drug target for Alzheimer’s.
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New humanised mouse model developed
Researchers have announced a humanised mouse model which can be used in drug development processes.
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Research shows pancreatitis biomarker linked to pancreatic cancer
A study has discovered that a biomarker associated with pancreatitis is involved in its development to pancreatic cancer.
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Neurodegeneration enzyme identified in mouse models
A new study has found an enzyme in the brains of mice models which induces Parkinson’s, suggesting future drug target.
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Gene discovery could make cancer therapies more effective
A recent study has identified the DBC1 gene which leaves cancer cells more exposed to therapies.
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Research identifies cells which contribute to inflammatory diseases
A new study has shown that there are two populations of cells in the gut which leads to drug development potential.
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New model found to improve drug development in pre-clinical trials
Researchers have successfully created a multi-organ in vitro model to test toxicity and efficacy of drugs.
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Study identifies two enzymes which protect tumour cells
Researchers have found an enzyme and its counterpart which inhibit T-cells from attacking tumour cells.
