A simple co-culture assay that can assess anti-tumour T-cell cytotoxicity via luminescence and flow cytometry has been created.
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Whitepaper: Evaluation of the analytical performance of the AQUIOS CL flow cytometer in a multi‑centre study
This whitepaper from Beckman Coulter evaluates the analytical performance of the AQUIOS CL flow cytometer in a multi‑centre study.
The World Health Organization (WHO) identifies leishmaniasis as a neglected tropical disease for which new treatments are vitally needed. Leishmaniasis primarily affects people in South America, East Africa and Asia, especially those weakened by malnutrition and poverty. To help those with this disfiguring and potentially life-threatening parasitic disease, the European…
We have entered a new era of drug discovery where the use of advanced cell models such as multi-cellular co-cultures, stem cells and CRISPR-based screens can lead to the next generation of therapeutics.
Not every step of CAR T-cell manufacturing can be tightly regulated, introducing some significant quality control challenges for companies developing CAR T cancer therapies
Biologics represent a growing class of drugs with indications in oncology, chronic inflammation, and autoimmune diseases.
Article: Immuno-oncology: Pushing the frontier of discovery through advanced high throughput flow cytometry
Immuno-oncology (IO) is increasingly prized as an effective therapy in cancer management.
No tumour prevails on its own. Rather, every tumour needs a community to thrive.
Flow cytometry is a common technique used to identify different immune cell types in mixed population samples such as peripheral blood or tissue samples.
There is still much to be done regarding how training is delivered and monitored in core technologies such as flow cytometry. Here, Derek Davies outlines the approaches his team at The Francis Crick Institute are taking to train users of such technologies to ensure quality data is obtained and best…
This issue includes an investigation into utilising recombinant antibodies for research, a highlight on protein design using computational methods and an examination of the advances in genomic medicine. Also in the issue are articles on next generation sequencing and upstream bioprocessing.
Sartorius debuts their new product, the Intellicyt iQue3, at this year's CYTO® conference and exhibition.