podcasts
Episode 1 – Dr Sri Gopal, Janssen Pharmaceuticals
Listen along to learn more about drug development for schizophrenia from Dr Sri Gopal, Head of Psychiatry R&D for Janssen!
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In Vivo
news
Nanoparticle vaccine shown to block range of flu strains in pre-clinical study
A new vaccine formulated with nanoparticles protected animal models from a variety of seasonal and pandemic influenza strains.
article
Identifying a novel treatment for heart attacks
Professor David Merryman explains how his team targeted the serotonin 2B receptor in animal models to preserve cardiac function six weeks after a heart attack.
news
Polymerised oestrogen provides neuroprotection in pre-clinical study
The polymerised form of oestrogen has shown success in mice at preventing further damage to the spinal cord after injury.
news
Cannabinoids could reduce essential tremors in patients
A synthetic cannabinoid has shown promise as a treatment for involuntary tremors by activating astrocytes in mouse models.
news
Chemical cocktail creates new avenues for generating muscle stem cells
A combination of chemicals has shown promise in pre-clinical studies to produce muscle stem cells, giving hope for regenerative medicine.
news
Rhesus macaque model of Alzheimer’s disease developed
Scientists have developed a model of the early stages of Alzheimer's disease in rhesus macaques to better test new treatments.
news
CRISPR-dead Cas9 could offer non-addictive treatment for pain, study shows
A new CRISPR gene therapy for chronic pain has been shown in mice to temporarily repress a gene involved in sensing pain.
news
Potential peptide to treat multiple sclerosis passes toxicology test
A peptide that could treat multiple sclerosis caused no neurotoxicity or cardiotoxic effects in zebrafish, a study has shown.
news
Researchers identify antibodies with potent effects against malaria
Six antibodies specific to the circumsporozoite protein of the malaria parasite have shown promise as therapeutic interventions, a study has shown.
news
Engineered stem cells shown to target breast cancer that metastasises to brain
A team have shown that a tumour-suppressing and killing molecule delivered to the brain by stem cells has been successful in mice.
news
Reversible male contraceptive shows promise in pre-clinical studies
Researchers have discovered the the compound triptonide is safe, effective and reversible as a male contraceptive in animal models.
news
Vaccine strategy developed to fight urinary tract infections
Researchers have shown that administering a urinary tract infection vaccine directly to the bladders of mice helped them to effectively fight bacteria.
video
SARS-CoV-2 vaccines: an interview with Payton Weidenbacher
DTR's Victoria Rees interviews Payton Weidenbacher from Stanford University, who discusses a new potential SARS-CoV-2 vaccine that the team he works on developed using nanotechnology.
news
Experimental mAb subdues type 1 diabetes in laboratory mice
A monoclonal antibody given to mice reversed type 1 diabetes by suppressing the actions of glucagon, a study has shown.
