Informatics

Sickle cell drugs could be tested with help from new computer model

23 August 2019 | By Rachael Harper (Drug Target Review)

New computer model that simulates the way red blood cells become misshapen by sickle cell disease could identity promising drug candidates.

Beyond the phenotype: using AI to better understand disease

19 August 2019 | By Victoria Rees (Drug Target Review)

Claus Bendtsen at AstraZeneca reveals how AI can be used to improve our understanding of disease, to help identify the causes of conditions and aid in drug discovery.

New model predicts cognitive decline two years ahead

6 August 2019 | By Rachael Harper (Drug Target Review)

Researchers hope the system can choose the right patients to enroll in clinical trials, to speed discovery of drug treatments.

Whitepaper: CD4+ T-Cell Subsets

22 July 2019 | By Bio-Techne

CD4+ T-cells play a central role in directing adaptive immune responses against invading microbial pathogens.

Sartorius debuts the Intellicyt iQue3 at CYTO^® 2019

8 July 2019 | By Sartorius

Sartorius debuts their new product, the Intellicyt iQue3, at this year's CYTO® conference and exhibition.

Whitepaper: The essential guide to managing laboratory samples

8 July 2019 | By Titian Software Ltd

Mosaic Sample Management is Titian Software’s comprehensive, customisable, modular software product to control and monitor all aspects of sample storage, preparation and delivery.

Titian Software Ltd

Video: Ethical and regulatory use of biospecimens in the EU

1 July 2019 | By BioIVT

Unique considerations surrounding the bureaucracy and oversight in the use of human biospecimens in the European Union.

High-res 3D structure of proteins inside living eukaryotic cells determined

3 June 2019 | By Drug Target Review

Nuclear magnetic resonance measurement and state-of-the-art computational science reveal protein structures in higher eukaryotic cells.

New mass spectrometry system for finding potential drugs

29 March 2019 | By Drug Target Review

New method for computational mass spectrometry will speed up the discovery of natural products that could be used in medicines...

Drug discovery from the age of information to the age of intelligence

20 March 2019 | By Jeff Martin (Head of Compound Management - Alkermes Inc.)

Data drives drug discovery, yet it continues to be among the biggest challenges faced by the industry.1 Experiments are often not repeatable and data interpretation is subject to the biases and limitations of human beings.

Informatics In-Depth Focus 2019

15 March 2019 | By Drug Target Review

In this In-Depth Focus: AI-driven automated chemistry as a tool to accelerate drug discovery, and a look at network-driven drug discovery

Drug Target Review – Issue 1 2019

14 March 2019 | By Drug Target Review

In this issue: AI-driven automated chemistry as a tool to accelerate drug discovery processes, the shifting landscape of immuno-oncology, and how lipid molecules provide an insight into biological research.

Network-driven drug discovery

14 March 2019 | By Alan Whitmore - e-therapeutics Plc, Jonny Wray - e-therapeutics Plc

Target-driven drug discovery, in which the starting point is a specific protein target hypothesised to play an important role in disease, has been the dominant paradigm for the last few decades. However, phenotypic-driven drug discovery, which does not rely on a specific target hypothesis, is starting to regain traction for…

Whitepaper: The most important mouse in the world: the utility and applications of C57BL/6 models

10 January 2019 | By Taconic Biosciences

Learn everything you need to know about the most widely-used mouse in biomedical research with this free whitepaper.