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Molecular Targets

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Ultrathin endoscope captures neurons firing deep in the brain

28 March 2018 | By Dr Zara Kassam (Drug Target Review)

A new fibre-based endoscope, tested in mice, poised to bring new insights into brain function...

news

Extracellular vesicles could be personalised drug delivery vehicles

15 March 2018 | By Drug Target Review

Researchers developed an approach and platform to create large amounts of fillable and targeted nanovesicles to deliver drugs to tumours in mice...

news

HIC1 protein may protect against intestinal disease

26 February 2018 | By Dr Zara Kassam (Drug Target Review)

Scientists find molecular link between Vitamin A derivative and mouse intestinal health...

news

Small molecule could make a big difference for arthritis patients

13 February 2018 | By Drug Target Review

Scientists have discovered a molecule that enhances cartilage regeneration and decreases inflammation.

Researchers identify new melatonin-based molecular targets for design of new drugs against Parkinson's

news

Researchers identify new melatonin-based molecular targets for design of new drugs against Parkinson’s

15 January 2018 | By Drug Target Review

A team of scientists has published the results of a new breakthrough in molecular mechanisms of the anti-parkinsonian activity of melatonin.

news

CXCR4 receptor provides therapeutic target for ovarian cancer

5 January 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have described a key cellular receptor in the processes of metastasis in ovarian cancer, the findings may lead to the use of CXCR4 inhibitors as a therapeutic target...

whitepaper

Scientific poster: Developing protein: Protein Interaction (PPI) assays with AlphaLISA and LANCE TR-FRET

2 January 2018 | By Catherine Lautenschlager (PerkinElmer), Daniel Cardillo (PerkinElmer), Matthew Reuter (PerkinElmer)

In this scientific poster, PerkinElmer demonstrates the ease and utility of using AlphaLISA® and LANCE® TR-FRET homogenous assay forms for studying PPIs.

whitepaper

Application note: Performing NanoBRET with the Varioskan LUX multimode reader

13 December 2017 | By Thermo Fisher Scientfic

In this paper, Thermo Fisher Scientific aim to assess the performance of Thermo Scientific Varioskan LUX when running NanoBRET.

news

Charles River announces success of integrated discovery project with ENYO Pharma

29 November 2017 | By Charles River Laboratories

Capture compound mass spectrometry technology enables target identification...

news

Charles River announces expansion of in vitro oncology services

30 October 2017 | By Charles River Laboratories

Partnership with InSphero provides additional 3D solutions...

news

Cell surface protein may offer target in treating childhood cancers

12 September 2017 | By Dr Zara Kassam (Drug Target Review)

Immunotherapy drug candidate could be potent weapon against neuroblastoma and other paediatric malignancies...

news

How receptors for medicines work inside cells

6 September 2017 | By Dr Zara Kassam (Drug Target Review)

G protein-coupled receptors are the key target of a large number of drugs, scientists have now been able to show more precisely how these receptors act in the cell interior...

news

PerkinElmer launches new IVIS® Lumina™ S5 and Lumina X5 systems for high throughput in vivo imaging

6 September 2017 | By PerkinElmer

Advanced 2D imaging and analysis help scientists rapidly trace anatomical and molecular aspects of diseases to advance drug discovery...

news

New technique speeds up chemical screening

23 August 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have developed a high-throughput technique that can determine if a chemical has the potential to activate key genes in seconds...

news

Researchers identify powerful pain reliever

17 August 2017 | By Dr Zara Kassam (Drug Target Review)

A team of scientists have discovered what they say is a powerful pain reliever that acts on a previously unknown pain pathway...

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Molecular Targets