Incorporating microglia into brain organoids
iPS-cell-derived microglia in brain organoids have enabled scientists to understand early brain development and microglia-associated disease.
List view / Grid view
iPS-cell-derived microglia in brain organoids have enabled scientists to understand early brain development and microglia-associated disease.
Researchers designed the first magnetoelectric material that precisely stimulates neurons to treat nerve damage.
New research reveals capillary cells and neurons work together to ensure memory formation and storage.
Human derived induced pluripotent stem cells (hiPSCs) have revolutionised research and are increasingly used for toxicology screening and disease modelling. Early detection of neurotoxicity induced by potential new therapies is a major challenge, and hiPSC-neuronal cells may provide a solution. These cells demonstrate considerable promise for uncovering drug-induced perturbations to…
The intricate control of our bodily movements relies on a network of neural pathways connecting the brain and spinal cord. Key among these pathways is the transmission of commands from neurons in the cerebral cortex to motor neurons in the spinal cord, which in turn activate muscles, enabling fluid motion.…
Using genetically modified human neural stem cells (hNSCs), researchers demonstrated that targeted manipulation of a specific gene expression within hNSCs can facilitate the restoration of damaged neural circuits and recovery of locomotor functions.
Activation of the Hedgehog signalling pathway through cilia holds promise for promoting cartilage repair and overcoming growth plate injuries.
New study uncovers role of a neuronal protein kinase called mitogen- and stress-activated protein kinase 1 (MSK1) in mediating the cognitive benefits of environmental enrichment.
New US research underlines the relationship between substance use and significant modifications to an inhibitory brain circuit, resulting in decreased cognitive flexibility
Researchers from the Human Brain Project (HBP) and collaborating institutions have made significant strides in understanding the distribution of receptors in the brain. Through a comprehensive mapping study, they discovered two distinct gradients of receptor expression per neuron in the cortex, shedding light on its organisation and functionality.
Neurotransmitter receptor patterns define key organisational principles in the brain, UK scientists have discovered.
US researchers have uncovered a novel method using a tool used to visualise ion channels in mechanosensory neurons.
New imaging approach reveals that changes in retinal microcirculation may indicate cerebrovascular diseases that involve reduced blood flow.
Researchers from Australia explore how viruses can alter brain cells, and thus the functions of our nervous system, leading to neurological symptoms.
US researchers uncover that certain nerve cells that have the capacity to regrow, are necessary for axon regeneration, providing hope for conditions like blindness and paralysis.