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Protein

New Alzheimer’s animal model more closely mimics human disease

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New Alzheimer’s animal model more closely mimics human disease

5 December 2017 | By Drug Target Review

Researchers have found that amyloid-? facilitates the interaction between the plaques and abnormal tau.

news

GDF6 gene associated with metastatic melanoma

4 December 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have revealed a protein active during early embryo development called GDF6 plays a primary role in metastatic melanoma...

Protein associated with ALS points to possible targets for therapeutic intervention

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Protein associated with ALS points to possible targets for therapeutic intervention

4 December 2017 | By Drug Target Review

Scientists may have found possible targets for therapeutic interventions in the fight against Lou Gehrig’s disease.

Scientists visualise structure of key DNA repair component

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Scientists visualise structure of key DNA repair component

1 December 2017 | By Drug Target Review

The ATR protein has been imaged at ‘near-atomic resolution’, providing greater insight into its activation in DNA repair.

news

Lung tumours communicate with bones to progress disease

30 November 2017 | By Drug Target Review

Scientists at Massachusetts General Hospital (MGH) have identified how a type of lung cancer co-opts a portion of the immune system via bone marrow to increase tumour progression.

news

Scientists make key development in understanding type-2 diabetes mechanism

29 November 2017 | By Drug Target Review

Scientists at the University of Geneva (UNIGE) have deciphered the mechanisms that link obesity with type-2 diabetes at the cellular level, thus explaining the reasons behind an association that is already well known.

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RT-QuIC testing detects prion protein in the skin of CJD patients

23 November 2017 | By Dr Zara Kassam (Drug Target Review)

Scientists have detected abnormal prion protein in the skin of patients that have died from Creutzfeldt-Jakob disease...

news

AFM-CRISPR technique used to map DNA mutations

21 November 2017 | By Dr Zara Kassam (Drug Target Review)

Nanomapping technology may transform the way disease-causing genetic mutations are diagnosed and discovered...

news

Reducing TIA1 improves nerve cell health in Alzheimer’s disease

20 November 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have described a unique model for the biology of Alzheimer's disease which may lead to an entirely novel approach for treating the disease...

news

CXCL5 protein may protect against coronary artery disease

17 November 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have identified a possible genetic basis for coronary artery disease...

news

Proteome of the human heart mapped for the first time

15 November 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have compiled an atlas of the heart to identify differences between healthy and diseased cells...

news

SORLA protein protects against Alzheimer’s disease

7 November 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have identified a new protective function for a brain protein genetically linked to Alzheimer's...

news

Starving a childhood brain tumour of glutamine, may improve the effect of chemotherapy

1 November 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have shown that starving a childhood brain tumour of the amino acid glutamine may improve the effect of chemotherapy...

news

Blood test developed to diagnose ovarian cancer

1 November 2017 | By Dr Zara Kassam (Drug Target Review)

Non-invasive diagnostic tool measures circulating microRNAs to predict ovarian cancer with specificity...

news

FT4 hormone levels associated with coronary artery disease and death

31 October 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have indicated that high levels of a thyroid hormone FT4, are associated with coronary artery disease...

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