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Proteomics

New Alzheimer’s animal model more closely mimics human disease

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New Alzheimer’s animal model more closely mimics human disease

5 December 2017 | By Drug Target Review

Researchers have found that amyloid-? facilitates the interaction between the plaques and abnormal tau.

news

DNA mutations shed in blood predicts response to immunotherapy

2 December 2017 | By Dr Zara Kassam (Drug Target Review)

Blood sample, or liquid biopsy, can reveal which patients will respond to checkpoint inhibitor-based immunotherapies...

news

RT-QuIC testing detects prion protein in the skin of CJD patients

23 November 2017 | By Dr Zara Kassam (Drug Target Review)

Scientists have detected abnormal prion protein in the skin of patients that have died from Creutzfeldt-Jakob disease...

news

Alzheimer’s Tau protein forms toxic complexes with cell membranes

22 November 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers identify the sequence and structural factors that drive Tau interaction with membranes...

news

AFM-CRISPR technique used to map DNA mutations

21 November 2017 | By Dr Zara Kassam (Drug Target Review)

Nanomapping technology may transform the way disease-causing genetic mutations are diagnosed and discovered...

news

Reducing TIA1 improves nerve cell health in Alzheimer’s disease

20 November 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have described a unique model for the biology of Alzheimer's disease which may lead to an entirely novel approach for treating the disease...

news

CXCL5 protein may protect against coronary artery disease

17 November 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have identified a possible genetic basis for coronary artery disease...

news

Proteome of the human heart mapped for the first time

15 November 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have compiled an atlas of the heart to identify differences between healthy and diseased cells...

news

SORLA protein protects against Alzheimer’s disease

7 November 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have identified a new protective function for a brain protein genetically linked to Alzheimer's...

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CXCR7 receptor reveals potential therapeutic target to reduce brain inflammation

6 November 2017 | By Dr Zara Kassam (Drug Target Review)

CXCR7 receptor identified as a potential therapeutic target for controlling multiple sclerosis, Parkinson's and AIDS...

news

Blood test developed to diagnose ovarian cancer

1 November 2017 | By Dr Zara Kassam (Drug Target Review)

Non-invasive diagnostic tool measures circulating microRNAs to predict ovarian cancer with specificity...

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FT4 hormone levels associated with coronary artery disease and death

31 October 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have indicated that high levels of a thyroid hormone FT4, are associated with coronary artery disease...

news

Modulating FAP may impede pancreatic cancer

30 October 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers offer a promising target for future therapies that could potentially root out well-hidden metastatic cancer lesions...

news

gp120 protein shows promise in HIV vaccine design

30 October 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have developed a vaccine candidate that spurs animals to produce antibodies against protective sugars of multiple HIV strains...

news

Mature B lymphocytes accelerate the healing of acute and chronic wounds

27 October 2017 | By Dr Zara Kassam (Drug Target Review)

Direct application of immune cells speeds and improves healing of acute and chronic wounds in animal models...

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Proteomics