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Novel biomaterial could be used to accelerate bone regeneration
In lab conditions, a new biomaterial was able to accelerate bone regeneration by boosting an immune response that encourages repair.
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Research & Development
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Link identified between COVID-19 and onset of diabetes
New research indicates COVID-19 could trigger the development of diabetes in healthy people, prompting experts to establish a registry for COVID-19 and diabetes data.
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Naphthalene-based PLpro inhibitors show potential as COVID-19 therapeutics
A group of small molecules called naphthalene-based PLpro inhibitors have been shown to block the activity of a SARS-CoV-2 protein, demonstrating potential as COVID-19 therapeutics.
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Compound from clams combats many common infections from parasites, finds study
A compound called tartrolon E, a byproduct of bacteria from shipworms, has been identified as researchers with the potential to fight and kill several parasites, including Cryptosporidium.
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SARS-CoV-2 immunodominant epitopes identified as vaccine candidates
Researchers have analysed the SARS-CoV-2 proteome to reveal seven promising immunodominant epitopes that could aid in the development of a COVID-19 vaccine.
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What immuno-oncology research can tell us about COVID-19
Dr Jing Watnick discusses how lessons learnt from cancer immunotherapy treatments could be applied to the development of COVID-19 therapies.
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Rod-shaped microparticles could improve immune system response to COVID-19
Researchers have suggested that neutrophils, which contribute to the development of ARDS in COVID-19 patients, could be diverted from the lungs by rod-shaped particles in a new form of treatment.
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Cancer drug could be used to treat Rett syndrome, finds study
Researchers have found that a compound named JQ1, an experimental cancer drug, extends the life of mice with Rett syndrome.
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Technique to synthesise anticancer compound FE399 developed
A team has successfully created a new method to artificially produce FE399, a compound known to induce apoptosis in cancer cells.
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Researchers develop a novel respiratory system simulator
Scientists reveal their reliable and tuneable simulator created using swine lungs, synthetic actuators and artificial muscles.
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Study identifies pathway responsible for blood-brain barrier impairment in Alzheimer’s
The team found that the expression of the APOE4 gene variant in pericytes caused amyloid plaque formation in a blood-brain barrier model.
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Investigational anti-SARS-CoV-2 molecules show efficacy in pre-clinical studies
Pre-clinical testing of the COVIDTRAP™ (STI-4398) protein and STI-1499 antibody reveal they can inhibit SARS-CoV-2 from infecting cells.
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A new vision: restoring eyesight using a novel gene therapy technique
Scientists created a technique to give photoreceptors infrared-light sensitivity, allowing the animal models to see infrared heat signatures.
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Researchers suggest animal experiments may be too standardised to be reproducible
Experts suggest that increasing biological and conditional variations in their experiments could not only make them more reproducible but also reduce the total number of animals required.
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TMPRSS2 inhibitors, Bromhexine, Aprotinin, Camostat and Nafamostat as potential treatments for COVID-19
Arsalan Azimi explains why inhibiting TMPRSS2 with clinically proven protease blockers could work as a therapeutic strategy against COVID-19.
