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Neuronal link between chronic pain and depression discovered
The mechanism in the brain connecting chronic pain and depression could lead to treatments for both, according to researchers.
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Scientists discover unique imaging technique to view synapse proteins
Researchers in the US have devised a new way to clearly image proteins located in synapses, which they hope will faciliate future treatment for diseases associated with blocked gene expression.
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A biosynthetic pathway to identify new drug candidates
A new process for identifying and biosynthesising drug candidates has been discovered by researchers at the Carl R Woese Institute for Genomic Biology.
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Researchers find DNA therapy could treat patients with DMD
A study has revealed that using DNA-like molecules to repair gene mutations in models could act as a successful therapy for patients.
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Novel CAR T-cell therapy for leukaemia and lymphoma
Scientists in the US have developed a promising new CAR T-cell therapy that targets the BAFF-R protein, which has demonstrated superior cancer destruction to existing FDA-approved CAR-T therapies.
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Researchers identify bacteria defence system mechanism
The process that bacteria use to defend themselves has been revealed by researchers, who also demonstrated how to activate the process.
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Possible target found for idiopathic pulmonary fibrosis treatment
A new study shows that using therapeutic antibodies to block the interleukin-11 protein can reverse idiopathic pulmonary fibrosis.
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Key protein in chikungunya virus replication identified
Researchers have found that the FHL1 protein plays a key role in chikungunya virus replication and pathogenesis.
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Mechanism behind glioblastoma survival revealed by study
Researchers have discovered the process that enables glioblastomas to avoid the effects of the immune system, presenting an immuno-oncology target.
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Method to reactivate ‘tumour suppressor’ genes discovered
A new method to reactivate 'tumour suppressor' genes switched off by cancer cells could lead to new targeted biotherapies for cancer.
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Device using small biomagnets could result in faster drug discovery
A new platform brings together genome editing with magnetic cell sorting to reveal new drug targets for cancer and regenerative medicine.
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Researchers reveal how fungi produce potential therapeutic compounds
A team has discovered that fungi use the Diels-Alder reaction to assemble new compounds that have potential pharmaceutical uses.
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New study shows insight into how cells maintain their identity
A new study shows the ways in which epigenetic mechanisms control the activity of genes and may have an impact on the future treatment of certain cancers.
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Chemotherapy resistance pathway identified for NSCLC
A study has discovered the mechanism behind NSCLC resistance to chemotherapy, which could improve treatment strategies for the condition.
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Dysfunctional insulin release mechanism identified
A mechanism has been identified which regulates the release of insulin from β-cells and could be used to develop new treatments for type 2 diabetes.
