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Pooling research and development resources to tackle emerging threats
Here, Sheraz Gul highlights some encouraging displays of industry co-operation that aim to counter the global threat posed by COVID-19.
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Screening
Medical screening is a strategy used to identify the possible presence of an as-yet-undiagnosed disease in individuals without signs or symptoms.
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Map of COVID-19 and human protein interactions reveals drug targets
Researchers have identified which SARS-CoV-2 proteins physically associate with proteins in human cells, revealing potential drug targets to treat the COVID-19 coronavirus.
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Lab Automation In-Depth Focus 2020
In this in-depth focus are features on the best data management options currently available and how the future of drug discovery will be connected and fully automated.
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Article: Five questions about the future of IoT in the laboratory
Gilson interviews Steve DeCabooter, Director of Product Information Platforms, about the growing role of connected tools and systems in the lab.
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Assays In-Depth Focus 2020
Included in this In-Depth Focus are articles on why human tissue models are best for testing nephrotoxicity and how genetic and pharmacogenomic testing can improve healthcare options.
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New compound could alleviate side effects of antidepressant drugs
Researchers have revealed a new substance that can bind well to serotonin transporters, offering a potential way to lessen the side effects of antidepressant therapies.
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Researchers to screen compound library for antiviral drugs to combat COVID-19
Scripps Research has announced it will screen over 14,000 compounds to see if any present significant activity against COVID-19, for use in a therapeutic.
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Novel phage display technique could lead to new peptide-based therapeutics
Researchers have shown that incorporating noncanonical amino acids (ncAAs) in phage display expands the range of peptides it can identify.
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Infographic: How PipettePilot® integrates with SciNote
Seamlessly track, record, and share your protocol and results with Gilson’s TRACKMAN® Connected and the SciNote digital lab notebook.
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Developing a COVID-19 testing kit using RNA detection
The developers of an RNA imaging technology are using it to create a COVID-19 coronavirus testing kit, able to recognise the viral genome.
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High-throughput screening used to analyse AAV vector libraries
Researchers have used high-throughput screening on AAV vector capsid libraries to identify which ones are best for certain gene therapies.
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Where could bioengineering and technological advances take drug discovery?
Drug Target Review explores the findings of a recent review of molecular, cellular, multi-cellular and tissue engineering and modelling technologies for drug design.
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CRISPR RNA-targeted genetic screen could be used for COVID-19 therapy
A new Cas13 RNA screen has been used to establish guide RNAs for the COVID-19 coronavirus and human RNA segments which could be used in vaccines, therapeutics and diagnostics.
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Application note: Tools for cell therapy and immunoregulation
Multiple co-signalling molecules regulate T cell activation.
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Software able to screen up to 1.4 billion compounds developed
New in silico screening software has the capability to screen billions of compounds, with the hope of improving drug design and limiting side effects.
