news
In vitro hair follicle model grown in culture
Scientists have developed a new strategy to generate hair follicles in vitro with potential useful applications for treating hair loss, animal testing and drug screening.
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Screening
Medical screening is a strategy used to identify the possible presence of an as-yet-undiagnosed disease in individuals without signs or symptoms.
news
Pre-clinical trials show drug inhibits inflammasome in COVID-19 cases
Anti-inflammatory effects of niclosamide, observed in a new pre-clinical study, were due to inhibition of the inflammasome, a protein complex presented in the interior of defence cells.
news
Novel AI model could accelerate drug discovery and precision medicine
A new AI model can accelerate drug discovery by accurately predicting human response to novel drug compounds.
news
New mitochondrial disease identified in identical twins
Unlike other mitochondrial diseases, a newly discovered form leads to hyperactive mitochondria, causing patients to have low body weight despite excessive food intake.
news
New drug discovery offers method to identify metabolic condition therapies
Drug-initiated activity metabolomics screening discovers the metabolite myristoylglycine, that converts white fat cells to brown fat cells.
whitepaper
Application note: Afucosylated mAb expression & antibody efficacy
Sino Biological’s “FucoFree” eukaryotic expression system provides high-yield and high-throughput afucosylated monoclonal antibody (mAb) production.
news
New antibiotic could stop advance of resistant pathogens
Using computational screening, researchers have discovered an antibiotic called Dynobactin, that halts the advance of antibiotic-resistant bacteria.
webinar
Power up your LNP and AAV sample prep with Unagi
12 October 2022 | By Unchained Labs
Watch this on-demand webinar to see first-hand data results demonstrating the power and flexibility of Unagi for nucleic acids, LNPs and AAVs.
whitepaper
Whitepaper: Advancing drug discovery for neurodegenerative diseases
This whitepaper reviews the drug discovery progress for neurodegenerative diseases, focusing on promising candidates identified using iPSC technology.
news
New drug has potential to turn COVID-19 virus against itself
The Scripps Research team showed that a variation of an already FDA-approved therapeutic for neurological disease can block COVID-19 infection in animals.
whitepaper
Product hub: Targeted protein degradation – next-generation therapeutics
Helen Harrison, Director of Screening at Amphista Therapeutics, discusses targeted protein degradation (TPD) and the discovery of drugs in this area.
whitepaper
Application note: Flow cytometry platform
Compendium of iQue® advanced flow cytometry platform application posters: Antibody discovery and immuno-oncology.
news
New study demonstrates an in silico reaction screening strategy for reaction development
Through the novel screening strategy, the researchers were able to develop a suit of 48 reactions that produce compounds that are potentially useful for new drugs.
whitepaper
Application note: Fast-track antibody discovery: a high-throughput method for identifying and isolating rare secreting cells
Discover how picodroplet microfluidic technologies can identify and isolate 'hit' cells, quantify varying concentrations of antigen-specific antibodies and much more.
article
A high-throughput macrodomain assay to identify coronavirus drugs
In the search for a rapid, easy way to identify drugs to fight SARS-CoV-2, researchers from across the US came together to develop and apply a high-throughput ADP-ribosylhydrolase assay, ADPr-Glo. Here, Dr Veronica Busa and Dr Anthony Leung from Johns Hopkins University describe the ADPr-Glo assay and how it can be…
