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Gimap5 gene mutations found to trigger immune diseases
Scientists discovered how a gene mutation affects T cell function to promote immune disorders...
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Genomic tools reveal diverse behaviour in immune cells
New research from La Jolla Institute for Allergy and Immunology using single-cell transcriptome analysis yields greater understanding of the human immune system.
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APC-mimetic scaffolds could facilitate more effective precision immunotherapies
Amplifying patient-specific T cells outside the body could increase the efficiency of cancer immunotherapies...
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Immune cells dictate tumour progression
Analysing individuals' genotypes and immunotypes could yield customised treatments for prostate cancer...
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Researchers use AI technology to chart immune cell receptor
Johns Hopkins scientists have used a form of artificial intelligence to create a map that compares types of cellular receptors, the chemical ‘antennas’ on the surface of immune system T-cells.
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Application note: Screening for inhibitors of PD-1 and PD-L1 binding with AlphaLISA technology
In this application note, PerkinElmer demonstrate the utility of an AlphaLISA assay for screening biotherapeutic antibodies and compounds that block binding of human PD-1 and PD-L1.
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Lung tumours communicate with bones to progress disease
Scientists at Massachusetts General Hospital (MGH) have identified how a type of lung cancer co-opts a portion of the immune system via bone marrow to increase tumour progression.
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Synthetic T-cells engineered to combat cancer
Researchers have engineered T-cells in the laboratory to combat tumours...
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DNA-based Zika vaccine found effective at inducing immune response
A new generation DNA-based Zika vaccine is the first to demonstrate both safety and the ability to elicit an immune response against Zika in humans...
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Nanoparticles give disease-fighting properties to cells
A new biomedical tool has been developed using nanoparticles that deliver transient gene changes to targeted cells...
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Researchers find switch that turns on immune cells tumour-killing ability
Researcher have shown how a mRNA molecule known as Lethal-7 serves as a molecular control hub to direct the function of cytotoxic T lymphocytes...
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Tumours detected with sugar molecules
Scientists have synthesised a complex sugar structure that specifically binds to the tumour protein Galectin-1...
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Killer peptide helps eliminate resistant cancer cells
Scientists have identified a Par-4 amino-terminal fragment that is released by diverse therapy-sensitive cancer cells...
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New gene mutations found in white blood cells in rheumatoid arthritis patients
Finnish researchers have found that an accumulation of gene mutations, similar to those typically seen in the development of cancer, also occur in some patients with rheumatoid arthritis.
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Scientists uncover how sunlight on skin reduces eczema inflammation
A new study has identified how exposure to sunlight alleviates symptoms of eczema by triggering the release of a compound in the skin that dampens inflammation.
