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Novel ‘prodrug’ designed to eliminate cancer without harming healthy cells
US researchers discovered in a study in mice that augmented drug eliminates cancer cells without causing toxicity.
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Novel protein identified that contributes to tau neurotoxicity in Alzheimer’s disease
US researchers have identified a protein that interacts and enhances the spread of neurotoxic species of tau, which is primarily found in neurons that appear abnormal in the brains of Alzheimer’s disease patients.
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New MACHETE technique developed to slice into cancer genome
Sloan Kettering Institute (SKI) researchers have developed a new machete technique to slice into the cancer genome and study copy number alterations.
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Five recent CRISPR drug target discoveries
This article highlights five of the latest findings revealed using CRISPR that could be used in the development or design of new therapies.
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Webinar: Top tips for successful particle size analysis
Discover how Malvern Panalytical’s combination of analytical instrumentation and research services can take particle size analysis to the next level.
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SK bioscience collaborates with IVI to support global R&D
SK bioscience and IVI convened in consultative meeting to discuss cooperation for next pandemic and announced KRW3 billion donation to IVI to support advancement of global vaccine R&D
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Probiotic ‘backpacks’ show promise for treating IBD
US researchers have uncovered the uncapped potential that gut-friendly bacteria has for improving treatments of inflammatory bowel disease (IBD).
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SARS-CoV-2 blocked by antiviral substances discovered in South Korean plants
South Korean researchers identified two saponins there were highly effective in blocking the ability of SARS-CoV-2 variants to enter cells.
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Novel nasal vaccine strategy could improve COVID-19 protection
Australian researchers have tested a new nasal vaccine in mice, with the potential enhance protection against COVID-19.
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Is the Nile rat the new animal model for diabetes research?
US researchers, using genome sequencing, put forward the Nile rat as the new model organism for diabetes research.
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Green tea and resveratrol could be the next step for Alzheimer’s disease research
US researchers, using a 3D neural tissue model, found that compounds from green tea and resveratrol could diminish Alzheimer’s amyloid plaques in lab tests, with no side effects.
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Guide: Understanding an API and all its forms with XRPD
This Malvern Panalytical guide explores the use of Xray powder diffraction (XRPD) as a powerful tool to develop and improve pharmaceutical formulation.
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Is hydroquinine the answer to antimicrobial resistance?
In this exclusive Q&A, Dr Robert Baldock, Research Scientist at the University of Portsmouth, discusses the compound hydroquinine and how it could be used as an effective weapon against a pathogen that causes serious infections in humans, mostly hospital patients.
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Whitepaper: Unique solutions for drug discovery and development
Looking for solutions to resolve your unique challenges? We offer several customized products and services to move your discovery forward.
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Novel synthetic peptides could suppress formation of harmful amyloid aggregates
German researchers have designed peptides that bind to amyloidogenic proteins linked to Alzheimer’s and type 2 diabetes, to effectively suppress both cytotoxic amyloid aggregation and amyloid cross-accelerating interactions.
