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Therapeutics

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Immunotherapy could cure advanced pancreatic cancer

11 October 2018 | By Iqra Farooq (Drug Target Review)

Immunotherapy using 'educated' killer cells could be a potential cure for pancreatic cancer, with researchers eliminating all signs of cancer from mice...

news

PIEZO2, a molecular target for neuropathic pain

11 October 2018 | By Drug Target Review

Scientists at Scripps Research have identified the molecule in neurons responsible for tactile allodynia, a protein called PIEZO2...

news

Early treatment could reverse autistic behaviour in tuberous sclerosis

10 October 2018 | By Drug Target Review

Scientists may have found a sensitive time period where autism related social deficits could be reversed in tuberous sclerosis...

news

Micropeptide molecule restores heart function

10 October 2018 | By Drug Target Review

A micropeptide molecule that reverses structural and functional changes in the heart could be a promising target for gene therapy...

news

CRISPR technique identifies Alzheimer’s biomarker

10 October 2018 | By Drug Target Review

UEx researchers have identified a potential biomarker for Alzheimer's disease using the CRISPR gene editing technique to analyse brain samples...

news

Scientists create map of brain region linked to Alzheimer’s disease

8 October 2018 | By Drug Target Review

Scientists have mapped areas of the brain that are linked to Alzheimer's disease to deliver genetically-targeted drugs to specific neurons...

news

RNA-seq of 20,000 cardiac cells reveals heart disease insights

5 October 2018 | By Iqra Farooq (Drug Target Review)

RNA analysis of 20,000 cardiac cells from heart tissue in both ordinary and deceased mice showed an insight to the development of heart disease...

news

Chemotherapy and APOE4 linked to cognitive issues

4 October 2018 | By Iqra Farooq (Drug Target Review)

Both human and mouse models show that chemotherapy and APOE4 are linked to cognitive issues faced by patients who overcome cancer...

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SERDs molecules could spur a new class of drugs for breast cancer

4 October 2018 | By Drug Target Review

Stevens researchers design and develop a new class of molecules for breast cancer therapy...

news

Umbilical cord stem cells used for early repair of cleft palate

3 October 2018 | By Drug Target Review

Stem cells harvested from the umbilical cord after birth could lead to a therapy to treat cleft lip and palate without the traditional surgery...

news

Cancer immunotherapy researchers win Nobel prize

3 October 2018 | By Iqra Farooq (Drug Target Review)

Researchers from the US and Japan have received the Nobel prize in medicine for their development of cancer immunotherapy using PD-1 and CTLA-4...

news

Rare mechanism for ALL to relapse after CAR-T therapy

2 October 2018 | By Iqra Farooq (Drug Target Review)

A single leukemic cell has become resistant to CAR-T therapy after unknowingly engineered with the leukemia-targeting CAR lentivirus...

news

Cancer vaccine shows promise for HER2-positive cancers

1 October 2018 | By Drug Target Review

Treatment with a HER2-targeted therapeutic cancer vaccine provided clinical benefit to several patients with metastatic HER2-positive cancers...

news

‘Paintable’ chemotherapy for melanoma shrinks tumours

27 September 2018 | By Iqra Farooq (Drug Target Review)

A hydrogel incorporating transfersomes and chemotherapy drugs incorporated with some intravenous medication may be the best treatment for melanoma...

news

Sugar specific molecules show promising results for new allergy vaccine

27 September 2018 | By Drug Target Review

Using sugar molecules researchers have developed a new vaccine for hay fever that may reduce treatment times and increase the effectiveness of treatments...

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Therapeutics