Therapeutics

Anticancer drug as an alternative to liver transplant

17 August 2018 | By Drug Target Review

Mouse models showed promise when an anticancer drug was used to treat liver failure, resulting in liver regeneration and preventing liver related death...

Effective approach to optimising medicinal molecules

15 August 2018 | By Drug Target Review

Computational methods accelerates and automates the process of optimisation of candidate molecules before performing preclinical trials...

Recent advances in diagnostics and treatments – from small molecules to cellular therapies

14 August 2018 | By Bio-Techne

With recent advances in medicine, cellular therapies are one step closer to becoming a reality where re-programmed cells, tissues and organs can be used as therapeutic agents. This webinar discussed the journey of medical treatments from small molecule to cellular therapies...

Bio-Techne

Pushpanathan Muthuirulan

13 August 2018 | By

Research Associate, Harvard University

Autoimmune response drives vision loss in glaucoma

10 August 2018 | By Drug Target Review

New research shows that immune cells developed from early exposure to bacteria contribute to vision loss in glaucoma patients...

Drugs in development for cancer may also fight brain diseases

9 August 2018 | By Drug Target Review

PARP inhibitors show promise in preventing toxic accumulations of brain disease proteins in Penn research study...

Genes increasing the risk of triple-negative breast cancer identified

8 August 2018 | By Drug Target Review

Germ line genetic testing analyses blood samples and evaluates inherited genetic changes that increase the risk of certain cancers in an individual...

Reducing NOVA1 helps prevent tumour growth in lung cancer

8 August 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have identified a gene that when inhibited, reduced human non-small cell lung cancer tumours from growing...

CRISPR-Cas9 used to correct sickle cell–causing mutation

7 August 2018 | By Dr Zara Kassam (Drug Target Review)

Genome editing using the CRISPR-Cas9 system has tremendous promise for therapeutic correction of genetic errors in human cells...

Novel PET imaging could guide therapy for type 1 diabetes

6 August 2018 | By Drug Target Review

Since beta cells and neurological tissues have common receptors, researchers screened brain radioligands for their ability to identify beta cells...

New stem cell model to test treatments for neurodegenerative disorders

2 August 2018 | By Drug Target Review

The team found that astrocytes inhibit growth of precursor cells that become myelin, and speed up the neural network in the brain...

D-PDMP reverses hair loss and skin damage linked to fatty diet

2 August 2018 | By Dr Zara Kassam (Drug Target Review)

In a series of experiments, researchers have used an experimental compound to successfully reverse hair loss, hair whitening and skin inflammation...

Is acidity the weakness of cancer cells?

1 August 2018 | By Drug Target Review

Cancer cells proliferating in alkalinity should be more vulnerable in acidic environments, so decreasing the pH may result in decreased proliferation...

IKZF1 gene could improve cancer immunotherapy

31 July 2018 | By Dr Zara Kassam (Drug Target Review)

A gene that's associated with an autoimmune form of hair loss could be exploited to improve cancer immunotherapy...