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Vaccine

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Scientists uncover key that permits hepatitis C entry into cells

22 September 2021 | By Anna Begley (Drug Target Review)

A new study has identified a key protein on the surface of the hepatitis C virus that interacts with a receptor found on human cells.

article

Drug Target Review Synthetic Biology ebook 2021

22 September 2021 | By Drug Target Review

In this ebook, discover why CRISPR can aid the development of new drugs via loss-of-function screens and how the field of synthetic biology is likely to evolve within the context of health.

article

Drug Target Review Vaccine Development ebook 2021

22 September 2021 | By Drug Target Review

Within this ebook, find articles examining the role of telomerase for universal cancer vaccines and discussing potential targets for neurodegenerative disease vaccines.

article

Drug Target Review – Issue 3 2021

22 September 2021 | By Drug Target Review

In this issue, find articles exploring why CRISPR is useful for high-throughput drug discovery, how targeting telomerase may lead to universal cancer vaccines and a new study to identify therapeutics that can be repurposed against COVID-19. Also included are features on neuroscience, organoids and antibodies.

news

MEPs demand action plan to end animal testing in Europe

16 September 2021 | By Anna Begley (Drug Target Review)

MEPs have requested that the EU adopts new plans to phase out the use of animals in scientific research and testing, focusing on alternatives instead.

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Study suggests how to develop intranasal vaccines for COVID-19 and flu

30 August 2021 | By Anna Begley (Drug Target Review)

New research has explored the role of nasal bacteria to better develop intranasal vaccines for viruses such as COVID-19 and flu.

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Spike gene mutants could be used as novel COVID-19 vaccine

27 August 2021 | By Anna Begley (Drug Target Review)

SARS-CoV-2 Spike gene mutants may be developed into immunogens for new vaccines against COVID-19, a study in hamsters has shown.

news

Intranasal COVID-19 vaccine shown to be effective in animal models

26 August 2021 | By Anna Begley (Drug Target Review)

A nasal spray of the COVID-19 Vaccine Oxford/AstraZeneca was found to protect hamsters and monkeys against SARS-CoV-2 in an NIH study.

news

Scientists develop novel strategy for tuberculosis vaccine

25 August 2021 | By Anna Begley (Drug Target Review)

A research team have created a new strategy for developing an effective vaccine against a widespread form of tuberculosis.

news

CureVac and GSK COVID-19 vaccine shows promise in pre-clinical study

17 August 2021 | By Anna Begley (Drug Target Review)

CureVac and GSK's second-generation mRNA COVID-19 vaccine candidate, CV2CoV, demonstrated improved immune response in a pre-clinical study.

news

Artificial intelligence may reveal how microbiome affects vaccine response

6 August 2021 | By Anna Begley (Drug Target Review)

Researchers have been using artificial intelligence to study how the microbiome interacts with the human system to improve vaccine response.

news

Masitinib found to be an effective COVID-19 treatment in mouse model

3 August 2021 | By Anna Begley (Drug Target Review)

Scientists from the University of Chicago discovered that the drug masitinib inhibits the replication of SARS-CoV-2 in mice.

news

New “atlas” charts how antibodies attack COVID-19 Spike variants

26 July 2021 | By Anna Begley (Drug Target Review)

A new “atlas” has been created in the US that charts how 152 different antibodies attack the SARS-CoV-2 Spike protein.

news

Newly designed tumour vaccine could prevent cancer recurrence

9 July 2021 | By Anna Begley (Drug Target Review)

Scientists have used nanotechnology to develop personalised tumour vaccines which prevented cancer recurrence and metastasis challenges in mouse models.

news

Anticoagulant drug a possible strategy to treat COVID-19 variants

8 July 2021 | By Anna Begley (Drug Target Review)

Researchers in Australia have discovered a new site on the COVID-19 Spike protein that could be targeted by an anticoagulant drug.

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