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Most antibodies targeting SARS-CoV-2 use specific immunoglobulin subtype
Researchers reveal IgHV3-53 is the most common immunoglobulin mutation used to target the receptor binding domain on the SARS-CoV-2 spike protein.
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Vaccine
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Prophylactics for COVID-19 – known and unknown
This article outlines the ideal scientific research that should be conducted to design a prophylactic to combat COVID-19.
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Vaccine adjuvant provides long-lasting protection against HIV in monkeys
A vaccine adjuvant named 3M-052 was able to provide rhesus monkeys with protection against HIV for over a year, a new study reports.
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MMR vaccine could protect against COVID-19 sepsis, paper says
Researchers have suggested that the MMR live attenuated vaccine could be used to provide non-specific protection to patients against sepsis associated with COVID-19.
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Potential for Mycoplasma pneumoniae vaccine through lipoprotein removal, finds study
A new study has shown that effective and safe M. pneumoniae vaccine could be possible by removing certain lipoproteins from the bacteria.
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New genetically attenuated parasite gives hope for malaria vaccine
Using a genetically attenuated parasite (GAP) with a particular deleted gene, researchers have developed a new potential malaria vaccine that arrests at the late liver stage.
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SARS-CoV-2 immunodominant epitopes identified as vaccine candidates
Researchers have analysed the SARS-CoV-2 proteome to reveal seven promising immunodominant epitopes that could aid in the development of a COVID-19 vaccine.
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Computational approach identifies novel COVID-19 vaccine targets
Researchers used computational tools to identify regions of the SARS-CoV-2 virus that could potentially provide a safe and long-term immune response.
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Delivering a therapy to kerb COVID-19
Sheraz Gul explores current research developments to help treat and tackle the spread of COVID-19.
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Neoantigens: presenting new vaccine opportunities in immuno-oncology
Neoantigens have gained much interest in recent years, mainly due to their ability to elicit a strong, specific immune response. Nikki Withers spoke to two immunology experts to explore the progress being made and assess what remains challenging for cancer investigators working on these transformational therapies.
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Using scientific literature to aid the development of a safe and effective COVID-19 vaccine
Researchers in the US describe how they utilised previously published scientific literature to guide the design of their potential COVID-19 vaccine.
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White blood cells as a novel early indicator of vaccine efficacy
Researchers demonstrate that a subpopulation of circulating white blood cells can act as an early indicator of vaccine efficacy, with potential implications for COVID-19 drug development.
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Protective immunity to SARS-CoV-2 shown in non-human primates
Macaques were protected against SARS-CoV-2 infection both after an initial infection and vaccination with a prototype vaccine, researchers suggest humans could respond similarly.
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Analysis of immune response to SARS-CoV-2 gives hope for COVID-19 vaccines
A detailed analysis of the body's immune response to COVID-19 has revealed that it can recognise SARS-CoV-2 in many ways, meaning vaccines can be used to stop the spread of the virus.
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Adding RPL6 protein to vaccine prevents malaria in mice, find researchers
Researchers have shown that adding the RPL6 protein to malaria vaccines was successful at protecting mice against the condition.
