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App note: Characterizing neurotoxin modulation of Nav1.5 channels

Posted: 22 December 2015 | | No comments yet

In this application note, you will learn how you can evaluate ion channel modulation by neurotoxins in a high-throughput setting…

Neurotoxins play a critical role in understanding ion channel structure and function. Since they are highly specific to their targets, neurotoxins as a group also possess huge potential as drug candidates for a multitude of ion channel therapeutic strategies. Historically, direct electrophysiological characterization of neurotoxins in a high-throughput manner has been challenging.

Characterizing neurotoxin modulation of Nav1.5 channels

In this application note, you will learn how you can evaluate ion channel modulation by neurotoxins in a high-throughput setting using the IonWorks Barracuda® Plus Automated Patch Clamp System from Molecular Devices.

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