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Glycosylation is one of the most important post-translational modifications when developing new biologics. It has a considerable impact on product performance and variability and is therefore a critical quality attribute (CQA), influencing product safety and efficacy.
29 May 2020 | By Fluidic Analytics
Styrene–maleic acid (SMA) copolymers have become popular tools used in membraneprotein research as they can extract both lipids and membrane proteins from cellular membranes while preserving the bilayer structure of the membrane in so-called nanodiscs.
Parainfluenza 3 (PI3V) is a virus that causes respiratory diseases in calves, from the common cold to advanced pneumonia.
Potential drugs not only need to bind to their targets, they also need to remain bound for a specific amount of time in order to work efficiently.
Learn practical tips from eight Principal Investigators about how to start your own lab.
Learn how you could use high-content analysis for functional & phenotypic assays in your infectious disease research or drug discovery.
Advances in technology, such as the development of connected lab instruments, can integrate into workflows to help address reproducibility challenges.
No tumour prevails on its own. Rather, every tumour needs a community to thrive.
Scientists at Celgene Corporation developed a screening process incorporating the Octet® HTX system to identify pools and clones with higher concentrations of bispecific antibodies. Higher throughput was achieved from the multiple simultaneous measures possible on the Octet system and rapid assay times, such as binding optimisation in only 10 minutes.…
Connected lab tools that digitally record each step researchers make, like Gilson’s TRACKMAN® Connected, help create traceable, centralised data.
Wnt proteins have been extremely difficult to purify in an active state due to their hydrophobic nature arising from post translational lipid modifications.
Gilson interviews Steve DeCabooter, Director of Product Information Platforms, about the growing role of connected tools and systems in the lab.
Identifying next generation targets for cancer immunotherapy.
Seamlessly track, record, and share your protocol and results with Gilson’s TRACKMAN® Connected and the SciNote digital lab notebook.
Multiple co-signalling molecules regulate T cell activation.
