Neurofilament light chains detect Alzheimer’s damage before symptoms
22 January 2019 | By Drug Target Review
A simple blood test reliably detects signs of brain damage in people on the path to developing Alzheimer's disease...
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Alzheimer's
Nuclear tracers help assess new drugs for neurodegenerative diseases
21 January 2019 | By Dr Zara Kassam (Drug Target Review)
New nuclear medicine tracers could help medical researchers find a cure for Alzheimer's and other neurodegenerative diseases.
New tools accurately illuminates intracellular phase separation
30 November 2018 | By Drug Target Review
Researchers have made discoveries about the formation of cellular components called membraneless organelles and the key role these organelles play in cells...
MRI scans shows promise in predicting dementia
23 November 2018 | By Drug Target Review
Brain changes evident in scans before memory, cognitive decline...
New information on the pathological mechanisms of Alzheimer’s disease
21 November 2018 | By Drug Target Review
Researchers have indicated that the accumulation of pathological tau triggers a safety valve mechanism in the otherwise well-regulated cell membranes...
Protein sequencing method could transform biological research
24 October 2018 | By Drug Target Review
A team of researchers have demonstrated a new way to sequence proteins that are much more sensitive than existing technology, identifying individual protein molecules rather than requiring millions of molecules at a time
Immunotherapy targeting blood protein fibrin
16 October 2018 | By Iqra Farooq (Drug Target Review)
Targeting the fibrin protein could ensure that fibrin leaking through the blood-brain barrier does not cause inflammation or disease in the brain...
Scientists create map of brain region linked to Alzheimer’s disease
8 October 2018 | By Drug Target Review
Scientists have mapped areas of the brain that are linked to Alzheimer's disease to deliver genetically-targeted drugs to specific neurons...
Cryo-EM shows structure of TRPM2
25 September 2018 | By Iqra Farooq (Drug Target Review)
The structure of the protein TRPM2, a possible drug target, has been revealed for the first time by researchers at Van Andel Research Institute...
The molecular link between ageing and neurodegeneration
28 August 2018 | By Drug Target Review
Researchers have described the discovery of a molecular link between ageing and a major genetic cause of both ALS and FTD...
Study suggests viral connection to Alzheimer’s disease
25 July 2018 | By Drug Target Review
A first-of-its-kind study implicates another culprit in the path to Alzheimer's disease: the presence of viruses in the brain...
Epidemiologists highlight a link between Alzheimer’s and herpes
12 July 2018 | By Dr Zara Kassam (Drug Target Review)
A new commentary by epidemiologists supports the viability of a potential way to reduce the risk of Alzheimer's disease...
MicroRNA provides promise in search for simple, early test for Alzheimer’s
29 June 2018 | By Drug Target Review
Researchers have found early evidence that tiny snippets of microRNA may help with early detection of conditions such as Alzheimer's disease...
Genes linking Alzheimer’s and Down syndrome discovered
26 June 2018 | By Drug Target Review
Scientists are a step closer to understanding which genes are responsible for early-onset Alzheimer's disease in people with Down syndrome...
NIH-funded study finds new evidence that viruses may play a role in Alzheimer’s disease
25 June 2018 | By Drug Target Review
Analysis of large data sets from post-mortem brain samples of people with and without Alzheimer's disease has revealed new evidence that viral species, particularly herpesviruses, may have a role in Alzheimer’s disease biology.
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