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A study has demonstrated that inducing brain vessel pulsations helps to clear substances from the brains of mice, so could be used to stop amyloid-β build up in the development of Alzheimer’s.
A new study has found that damage caused by Alzheimer's allows toxins to enter the brain, further harming neurons.
A review has been published by experts in neurodegeneration research, detailing six ways to improve dementia research. This article investigates one of these suggestions, focusing on how we can improve drug target identification.
Researchers haved mapped the crystal structure of a protein to find out how a drug latches onto it.
New research has identified an enzyme which causes degradation of dendritic spines, pointing to a drug target for Alzheimer’s.
A simple blood test reliably detects signs of brain damage in people on the path to developing Alzheimer's disease...
New nuclear medicine tracers could help medical researchers find a cure for Alzheimer's and other neurodegenerative diseases.
Researchers have made discoveries about the formation of cellular components called membraneless organelles and the key role these organelles play in cells...
Brain changes evident in scans before memory, cognitive decline...
Researchers have indicated that the accumulation of pathological tau triggers a safety valve mechanism in the otherwise well-regulated cell membranes...
A team of researchers have demonstrated a new way to sequence proteins that are much more sensitive than existing technology, identifying individual protein molecules rather than requiring millions of molecules at a time
Targeting the fibrin protein could ensure that fibrin leaking through the blood-brain barrier does not cause inflammation or disease in the brain...
Scientists have mapped areas of the brain that are linked to Alzheimer's disease to deliver genetically-targeted drugs to specific neurons...
The structure of the protein TRPM2, a possible drug target, has been revealed for the first time by researchers at Van Andel Research Institute...
Researchers have described the discovery of a molecular link between ageing and a major genetic cause of both ALS and FTD...
