List view / Grid view
Researchers demonstrate that their novel small molecule, which activates the STING protein, supresses tumour growth and metastasis in a murine model of aggressive melanoma.
A new study conducted in Israel suggests that T cells’ ability to destroy skin cancer increases in the absence of T-cell regulators called SLAMF6.
Researchers have revealed that the WDR74 protein plays a key role in lung cancer and melanoma, including metastasis, indicating it may be a potential drug target.
An innovative new vaccine technique, which sensitises the immune system to the genetic signature of APOBEC mutations (often found in cancers), increases the efficacy of immunotherapies.
A study of published papers has revealed the importance of research into how the microbiome affects the development of melanoma.
A study has shown that long non-coding RNA called DIRC3 can block melanoma growth and could be used to identify new targets for skin cancer therapies.
Upregulation of the c-Cbl gene causes degradation of the immune checkpoint protein PD-1 and may provide a possible new avenue for cancer therapies, according to researchers.
Researchers have created a novel genetically engineered mouse model for the study of melanoma that they say is more efficient than traditional models.
Researchers have discovered that B cells aid T cells in fighting cancer, which could be an area of development for immunotherapies.
A study has found that removing a particular kind of macrophage enables the immune system to attack tumours, providing a potential drug target.
A protein discovery could lead to a new and highly potent immune-therapeutic drug for the eradication of cancers using natural killer cells.
Researchers have revealed a key inflammation mechanism that contributes to melanoma brain metastasis and could be a therapeutic target.
A study has found that signals from interferons can be blocked, allowing the immune system to attack tumours which provides a potential target.
A novel nano-vaccine has been developed which has proven effective in treating primary tumours and metastases that result from melanoma.
Researchers have found that fat cells transfer cytokines to melanoma cells, which transforms them into aggressive tumours, indicating a drug target for the condition.
