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GDF6 gene associated with metastatic melanoma
Researchers have revealed a protein active during early embryo development called GDF6 plays a primary role in metastatic melanoma...
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Melanoma
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B-cells promote melanoma progression and resistance to therapy
Depletion of B cells in the tumour micro-environment shows anti-tumour activity in patients with advanced metastatic melanoma...
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Gut microbes linked to immunotherapy response in melanoma patients
7 November 2016 | By Niamh Louise Marriott, Digital Content Producer
Patients with malignant melanoma are more likely to respond to immunotherapy treatment if they had greater diversity in their gut bacteria, according to...
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MSD acquires drug discovery company IOmet
12 January 2016 | By Victoria White
The acquisition includes IOmet's comprehensive preclinical pipeline of IDO (indoleamine-2,3-dioxygenase 1), TDO (tryptophan-2,3-dioxygenase), and dual-acting IDO/TDO inhibitors...
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New class of inhibitory compounds aid melanoma treatments
3 December 2015 | By Victoria White
Using cell cultures of melanoma, researchers showed that these acid ceramidase inhibitors make melanoma cells more prone to be killed...
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Intelligent biogel effective at delivering anti-cancer agents
20 November 2015 | By Victoria White
The technology has already been successfully tested in the laboratory. If it works in patients, the therapy could one day revolutionise treatment for many forms of cancer...
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MD Anderson’s expands its Moon Shots Programme
30 October 2015 | By Victoria White
MD Anderson's Moon Shots Programme is an unprecedented effort and novel organisational model designed to more rapidly convert scientific discoveries into life-saving advances...
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Lilly and ImaginAb to investigate imaging agent in immuno-oncology therapies
13 October 2015 | By Victoria White
ImaginAb will conduct preclinical research using its immune imaging agent, IAB22M2C, to detect T-cell trafficking, redirection and infiltration in response to Lilly oncology molecules...
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MedImmune and 3M partner to develop novel TLR agonist cancer therapies
25 September 2015 | By Victoria White
TLR agonists are promising agents that activate innate immune cells and enhance the visibility of cancer tumours...
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SAS1B discovery could fundamentally alter cancer treatment
10 September 2015 | By Victoria White
The SAS1B protein appears only on egg cells and cancer cells, and could serve as a target for tiny tracking probes created using monoclonal antibodies...
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Aspirin could boost cancer immunotherapy
4 September 2015 | By Victoria White
Researchers have shown that combining immunotherapy with aspirin or other COX inhibitors substantially slowed bowel and melanoma skin cancer growth in mice...
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Scientists discover why moles stop growing
6 August 2015 | By Victoria White
Researchers from the University of Pennsylvania have identified a major genetic factor that keeps moles in their usual non-cancerous, no-growth state...
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Immunocore and Lilly announce immunotherapy-based clinical trial collaboration in melanoma
29 June 2015 | By Victoria White
Immunocore and Lilly have entered into a collaboration to explore the utility of IMCgp100 in combination with galunisertib and merestinib in melanoma...
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Siemens and BioNTech cooperate on production of personalised cancer vaccines
26 June 2015 | By Victoria White
Siemens and BioNTech will work together on the construction of a fully automated and digitalised production site for BioNTech's personalised cancer vaccines...
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Novogen’s Anisina on track to enter the clinic in 2016
24 June 2015 | By Victoria White
Novogen has announced that its candidate cytotoxic chemotherapy drug, Anisina, has proved an effective anti-cancer agent in animals...
