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PAINS management: an open source model to eliminate nuisance compounds

4 December 2018 | By

High-throughput screening (HTS) technologies have enabled the routine testing of millions of compounds towards the identification of novel ‘hit’ molecules for therapeutic targets. Oftentimes in this drug discovery process, however, compounds that show promising activity in primary screens show no activity during subsequent hit qualification or progression efforts.

Application Note 2018 summary cover
Application Note 2018 summary cover
article

Application Notes supplement 2018

4 December 2018 | By

Researchers are always looking more effective and efficient ways of making their work more successful. In this supplement, some of our commercial partners share their data, detailing the application of their technology.