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The N439K mutation improves the interaction between SARS-CoV-2 Spike protein and the viral receptor ACE2 and eludes antibody-mediated immunity, say investigators.
In this whitepaper we explore some of the major bottlenecks in the development lifecycle and the current barriers to effective digital transformation.
Learn how Simple Western automated immunoassays screen degraders and IMiD compounds to quantify degradation activity, providing accurate DC50 and Dmax values.
Identifying allosteric modulators and biased agonists for clinically relevant GPCRs. Case Studies using Eurofins Discovery’s GPCR product solutions.
21 January 2021 | By Yokogawa Life Innovations
Watch our on-demand webinar and learn how image-based phenotypic screening relies on extraction of multivariate information from cells cultured in a large number of screened conditions. In this webinar, we explore the application of complex and biologically relevant model systems for drug screening, such as small intestinal organoids.
In this article, Drug Target Review’s Hannah Balfour discusses three of the latest developments in imaging for disease research and drug development.
Researchers have revealed how the most severe cases of G6PD deficiency occur, which could help scientists design new drugs for the disease.
A better understanding of the role of four-stranded DNA (G-quadruplex) could enhance cancer therapeutics, said the developers of the probes.
Using cryo-electron microscopy, researchers have observed the structure of a diarrhoea enteric adenovirus to see how it can survive the stomach.
Researchers have used force atomic microscopy to show the structural dynamics at ribosome stalk proteins when building new proteins.
This webinar from Bio-Techne demonstrates how to use a novel in vitro flow cytometry-based assay to monitor SARS-CoV-2 binding to ACE-2.
Discover how workflows are being accelerated to speed up the vaccine research and development process while maintaining safety and immunogenicity.
A new study suggests that inflammation and blood vessel damage may be the primary causes of neurological symptoms in COVID-19 patients, instead of the virus infecting the brain.
A new subspace mass spectrometry imaging method has enabled researchers to provide data sets exponentially faster.
Researchers show that neutralising antibodies targeting the SARS-CoV-2 Spike protein have four distinct structures.
