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Informatics

Drug Target Review – Issue #3 2015

21 September 2015 | By Drug Target Review

Included in this issue: Drug Development, Microfluidics, Proteomics, Ion Channels, GPCR, Imaging, Flow Cytometry, Enzymes

news

Dr Jeanette Wood joins Nuevolution as Scientific Advisor

21 September 2015 | By Victoria White

Dr Wood's expertise and experience to support Nuevolution in developing its pipeline in oncology, inflammation and immuno-oncology...

news

Selvita expands its operations into the US

21 September 2015 | By Victoria White

Appreciating the importance of the US biotechnology and pharmaceutical market, Selvita decided to come closer to its partners and clients and open a fully-owned US subsidiary, Selvita Inc...

Microfluidic technology: the next-generation drug discovery tool

article

Microfluidic technology: the next-generation drug discovery tool

21 September 2015 | By Kimberly Plevniak (Kansas State University), Mei He (Kansas State University)

Microfluidic miniaturisation, or the so-called ‘lab-on-a-chip’ concept, now encroaches on the fields of biology, medicine and pharmacology, and the nature of microfluidic technology (small volumes and high-throughput integration of fluid connections) means that it is outperforming conventional bench work. There has been an incredible need for microfluidic technology in the…

Flow cytometry: Not just a box in the lab

article

Flow cytometry: Not just a box in the lab

21 September 2015 | By Rachael Walker (Babraham Institute)

Undoubtedly, you will have noticed the increase in the number of publications utilising flow cytometry, heard it mentioned more in meetings and probably even been targeted by several companies trying to sell you their latest cytometer. The rapidly advancing technology behind the cytometer and an increase in applications that use…

article

SOMAscan™ assay: a vital proteomic tool in drug discovery

21 September 2015 | By SomaLogic

The SOMAscan™ assay is a highly multiplexed, sensitive, quantitative and reproducible proteomic tool for discovering biomarkers for drug discovery...

BioTek’s Synergy Neo2 Multi-Mode Microplate Reader

article

The importance of measuring drug target residence times

21 September 2015 | By BioTek

The Synergy Neo2 Multi-Mode Reader is designed to provide high temporal resolution in drug target kinetics applications...

article

Enzymes: Ubiquitin-specific proteases as druggable targets

21 September 2015 | By Anton Simeonov, Mindy Davis (National Institutes of Health)

In much the same way that kinases and phosphatases attach and remove phosphate groups from proteins to modulate their activity, there are a series of enzymes (E1, E2, E3) that add one or more ubiquitins onto a protein, as well as enzymes that remove them (deubiquitinases; DUBs), thereby regulating their…

news

Dementia Consortium funds project focusing on ALS and FTLD

16 September 2015 | By Victoria White

A team at the International Centre for Genetic Engineering and Biotechnology (ICGEB) will join forces with MRC Technology to take on the project...

news

Auspherix and Domainex expand antibiotics partnership

15 September 2015 | By

Since initiating the project in 2014, significant progress has been made towards the invention of new compounds with activity against both gram-positive and gram-negative bacteria...

news

Desktop Genetics raises £1.37M to accelerate development of DESKGEN

15 September 2015 | By Victoria White

DESKGEN allows researchers to expertly design and perform CRISPR-based genome editing experiments in virtually any cell line or species...

webinar

Immunology Screening on the iQue Screener

14 September 2015 | By IntelliCyt

Immunology Screening on the iQue Screener: Assays for Immune-Modulators and Immunotherapy...

news

Transatlantic partnership to develop treatments for pancreatic cancer

14 September 2015 | By Victoria White

The five-year programme will focus on the development of ‘nanomedicine’ in the treatment of pancreatic cancer, for which current treatment options are limited...

news

Cancer Research UK and MedImmune launch biotherapeutics research centre

14 September 2015 | By Victoria White

The new laboratory, opened in Cambridge, will focus on the discovery and development of novel biologic cancer treatments and diagnostics...

news

Researchers discover new group of antibiotics

14 September 2015 | By Victoria White

The potential new antibiotics are unlike contemporary antibiotics because they contain iridium, a silvery-white transition metal...

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Informatics