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Screening technique could accelerate and improve mRNA therapies
A new single-cell nanoparticle targeting-sequencing approach can measure the cellular uptake of lipid nanoparticles carrying mRNA therapies.
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Omics
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Chicken eggs used to produce SARS-CoV-2 antibodies
Researchers in the US have found that antibodies to the SARS-CoV-2 Spike protein can be produced in hen eggs.
video
Video: Did you know that ddPCR technology offers lower variability for viral titer determination?
Droplet Digital PCR (ddPCR) offers greater accuracy and precision in quantifying viral titer in gene therapies.
news
Whole exome sequencing predicts whether cancer patients will respond to immunotherapy
Researchers have developed a two-step approach using whole exome sequencing to focus on genes and pathways that predict whether cancer patients will respond to immunotherapy.
news
Scientists map networks of disease-associated immune genes
The new immune gene networks have implications for developing immunotherapies and understanding autoimmune diseases.
news
Building artificial Hox genes
Researchers have created artificial Hox genes using new synthetic DNA technology and genomic engineering in stem cells.
article
Whole genome sequencing in cancer research
A recent whole genome sequencing study has revealed hidden insights into the causes of cancer. In an exclusive article, Dr Andrea Degasperi from the Early Cancer Institute at the University of Cambridge, UK spoke to Drug Target Review's Ria Kakkad about the study's implications and the future of whole genome sequencing.
news
Soft nickases could be the future of safe, effective gene editing
Researchers in the US have developed a new CRISPR method for treating genetic conditions using nickases that they say is safer and more effective.
whitepaper
Infographic: Detecting Mycoplasma contamination in your cell culture with confidence
This infographic will explore Mycoplasma contamination in cell cultures and the best technologies for detection.
news
Dysfunctional gene leads to potentially treatable deafness
Researchers have found that inherited mutations in the MINAR2 gene causes deafness. The findings suggest that deafness could be treated with genetic therapies.
article
A multi-step analysis including GCI reveals novel insight into LPS translocation
Antibiotic resistance is one of the key health challenges of the future. In a new study, researchers have carried out a multi-step analysis to deliver insights into translocation of the hydrophobic and hydrophilic portions of the large lipopolysaccharide molecules through the outer membrane of Neisseria gonorrhoeae. This article summarises their…
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Antibody pipelines – the pharma perspective
Dr Erik Vernet, Director of Antibody Technology at Novo Nordisk, discusses antibody discovery and development workflows, including the role of informatics processes, in this Q&A.
news
Gene discovery indicates motor neurone diseases caused by abnormal lipid processing in cells
A new genetic discovery adds weight to a theory that motor neurone diseases are caused by abnormal lipid processing pathways inside brain cells.
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Providing new hope for rare disease using non-viral gene therapy
Viral vectors to deliver gene therapies are utilised by clinically approved therapies. However, this method is not the only option for advanced therapeutics. In this piece, Brent Warner, President, Gene Therapy at Poseida Therapeutics, discusses the balance between efficacy and safety in gene therapy, highlighting positive pre-clinical data for non-viral…
whitepaper
Whitepaper: CAR T-Cell analysis with modular antibodies using SpyTag protein ligation
Here Bio-Rad presents the generation of specific anti-CAR T-cell antibodies to show how CAR T-cell analysis benefits from our modular antibody assembly technology using SpyTag-SpyCatcher protein ligation.
