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Novel microfluidic and sequencing method enables epigenetic studies
A new microfluidic technology has been developed which can profile histone modifications with as few as 100 cells per assay.
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Can a computer help us find a treatment for COVID-19?
Researchers are utilising computers to aid in their investigations into a COVID-19 treatment. Here, we highlight three studies using simulations, calculations and AI to identify a drug to combat the coronavirus.
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Researchers observe how SARS-CoV-2 changes human cells after infection, revealing drug targets
Using mass spectrometry, researchers have shown how human cells are changed by infection from SARS-CoV-2, allowing the team to identify drug targets to prevent viral reproduction.
whitepaper
ebook: High-content analysis and infectious disease
Learn how you could use high-content analysis for functional & phenotypic assays in your infectious disease research or drug discovery.
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Chromatography and bioassays used to detect bioactive compounds in plants
Bioassays and thin-layer chromatography has been used by scientists to analyse molecules in plant extracts as a fast and cost-effective method for identifying new drug compounds.
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Establishing Alpha CETSA HT in primary screening
7 May 2020 | By PerkinElmer
High-throughput screening (HTS) cascades have evolved to ensure that high quality hits can be identified from large screening collections.
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Immuno-oncology assay market predicted to be worth $6bn by 2026
A rise in biotechnology R&D activities is expected to drive the growth of the immuno-oncology assay market, with a CAGR of 10.6 percent.
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Intravenous immunoglobulins, hyperimmunes and pandemic viruses
David Johnson of GigaGen discusses how recombinant forms of intravenous immunoglobulins (IVIG) could overtake current IVIG therapies and be used in the treatment of COVID-19.
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Three new assays to test COVID-19 antivirals developed
A series of three new assays to screen for drug compounds or proteins that combat the COVID-19 coronavirus has been developed.
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Collaboration to identify novel COVID-19 drug targets announced
Bringing together protein science, drug discovery experience and innovative technology, a new collaboration aims to identify novel drug targets for COVID-19.
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Researchers identify lead compounds for treatment of telomere diseases
Researchers investigating telomere dieases such as dyskeratosis congenita have found lead compounds that reverse cellular ageing in mouse models of the condition.
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Fundamental molecular research underpins our ability to combat COVD-19, says article
Ali Shilatifard’s article explains how investment in institutes performing molecular research is essential, as it is the foundation for all attempts to combat COVID-19 and other future pandemics.
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COVID-19 research indicates SARS-CoV-2 exploits immune defences to drive infection
A new study has revealed that less than 10 percent of respiratory and intestinal cells are susceptible to SARS-CoV-2 infection and expression of ACE2 receptors is driven by the body's immune response.
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High-throughput protocol for producing tetramer assay probes used to investigate COVID-19
The developers of a novel method to create immunological assay probes for screening T cells has leveraged their new protocol against COVID-19.
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Novel visualisation platform to aid understanding of COVID-19 strain evolution
The visualisation platform is being used to analyse how the SARS-CoV-2 virus causing COVID-19 is evolving and could be used to inform drug design.
