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Researchers reverse obesity in mice using CRISPR-Cas9

30 August 2019 | By Victoria Rees (Drug Target Review)

A study has used CRISPR-Cas9 to treat obesity and type 2 diabetes symptoms in mice, highlighting the potential use in humans.

news

Structure of crucial metabolic enzyme revealed by high-end microscopy

29 August 2019 | By Rachael Harper (Drug Target Review)

Scientists reveal the atomic structure and regulative mechanism of the metabolic enzyme transhydrogenase.

news

Unhealthy gut microbiomes in mice remodelled into more healthy ones

27 August 2019 | By Rachael Harper (Drug Target Review)

Scientists have shown that there are molecules to remodel the gut microbiome and turn an unhealthful gut into a more healthful one for the first time.

news

Immune cell function in cancer immunotherapy revealed

27 August 2019 | By Victoria Rees (Drug Target Review)

Researchers have discovered the roles that immune cells play in tumour growth and breast cancer immunotherapy which could aid in drug development.

article

Uniting humans and data: the role of AI in genomics

27 August 2019 | By Victoria Rees (Drug Target Review)

AI has applications in many areas of research, including genomics. Slavé Petrovski of AstraZeneca reveals how AI is used in the study of the human genome and how it may evolve in the future.

news

Researchers discover bronchospasms mechanisms using microdevice

26 August 2019 | By Victoria Rees (Drug Target Review)

A ‘bronchi-on-a-chip’ has been created by researchers to identify the processes of bronchospasms which could aid in respiratory disease therapies.

news

Organ-on-an-electronic-chip could be used in drug development

23 August 2019 | By Victoria Rees (Drug Target Review)

Researchers have created a new organoid model that can be used to study systems such as the heart and the effects of drugs on these cells.

news

Cyclisation reaction enables screening of macrocyclic compounds libraries

22 August 2019 | By Rachael Harper (Drug Target Review)

Libraries of more than 9,000 macrocyclic molecules below 1 KDa have been generated, small enough to cross cell membranes and reach targets.

news

Optofluidic chip platform developed for single molecule analysis

19 August 2019 | By Rachael Harper (Drug Target Review)

A new platform has enabled an unprecedented level of control over individual molecules and particles on a chip for high-throughput analysis.

news

New CRISPR technique could alter the way we look at brain diseases

16 August 2019 | By Fraser Owen (Drug Target Review)

Researchers may have fundamentally altered the way scientists study brain diseases with new CRISPR technology.

news

Experimental treatment slows prion disease

5 August 2019 | By Rachael Harper (Drug Target Review)

A new experiment has not only slowed the progression of the prion disease, scrapie, it also extended the lives of prion-infected mice

news

Molecular Devices introduces the FLIPR^® Penta system

2 August 2019 | By Molecular Devices

Molecular Devices, LLC, today announced the launch of the next generation of its FLIPR® Penta High-Throughput Cellular Screening System.

news

Motor neuron disease electrical signalling pathways mapped

1 August 2019 | By Victoria Rees (Drug Target Review)

A study has used EEG to investigate the neuron networks that act abnormally in the condition, providing a significant step in the search for treatments.

news

Newly discovered signal could lead to anti-cancer therapies

31 July 2019 | By Drug Target Review

Researchers have newly found that protein CD24 acts as a defensive signal and is used by cancer cells to protect themselves.

whitepaper

Application note: Monitoring Aggregation of Antibody-Drug Conjugates

30 July 2019 | By Enzo Life Sciences

Prediction of Aggregation Propensity and Monitoring of Aggregation of Antibody-Drug Conjugates (ADC).

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