SMCHD1 protein found essential to X chromosome inactivation
The structural protein is required for the chromosome to adopt a conformation that suppresses gene expression...
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Scientists decode ASCT2 protein as possible cancer drug target
Scientists in the Netherlands have investigated the structure of the human glutamine transporter ASCT2 in a bid to generate leads for cancer drug development.
Scientists create ‘genetic atlas’ of proteins in human blood
Researchers have created the first detailed genetic map of human proteins...
ImmunoPET imaging noninvasively pinpoints colitis inflammation
A novel PET imaging method shows promise for noninvasively pinpointing sites of inflammation in people with inflammatory bowel disease...
Arc protein ‘switch off’ essential for cognitive flexibility
An international team of scientists has discovered that memory, learning and cognitive flexibility depend on a 'switch off' of the Arc protein in the brain, which could enable us to better understand and combat neurological diseases that inhibit memory, such as Alzheimer's.
Novel gene in red blood cells may help adult newts regenerate limbs
Japan-US research collaboration has found that red blood cells that express a novel gene may contribute to adult newt limb regeneration.
Scientists link inflammatory signalling to atrial fibrillation
An international team of scientists have found that interfering with inflammatory signals produced by heart muscle cells might someday provide novel therapeutic strategies for atrial fibrillation.
LM11A-31 restores some bladder function after spinal cord injury
An experimental drug that blocks abnormal neural communication after spinal cord injury could one day be the key to improving quality of life by improving bladder function...
HIV vaccine elicits antibodies in animals that neutralise dozens of HIV strains
NIH study results represent a major advance for structure-based HIV vaccine design...
PROM microscopy analyses cellular focal adhesion dynamics
Researchers have developed a new form of microscopy that allows them to observe the formation and evolution of cell membrane focal adhesions…
Blood stem cells balance the immune system by teamwork
The human body’s blood stem cells produce approximately 10 billion new white blood cells – termed immune cells – every day. Scientists in the U.S. have now discovered that some blood stem cells pick up the slack should any others fail to achieve these levels.
APOE4 gene variant linked to Alzheimer’s
A study reveals why people with the APOE4 gene have a higher risk of the disease...
CRISPR approach could limit toxicity of CAR-T therapy in AML
New study uses CRISPR/Cas9 to make CD33 CAR T cells cancer-specific...
EMT activation in tissue growth is also at play in cancer metastasis
Scientists in the USA have added a new dimension to the understanding of how cells alter their communication with one another by means of epithelial mesenchymal transition (EMT) during development, wound healing, and the spread of cancer.
Researchers use blood serum markers to develop lupus risk index
Researchers have developed an index that identifies the risk for lupus based on the presence and amount of IgG and IgM antibodies and levels of C1q...
