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16 August 2016 | By Niamh Louise Marriott, Digital Content Producer
The drug development company will collaborate with the research centre on develoing microbiome-derived immunotherapies for cancer patients, to influence the efficacy of checkpoint inhibitors...
15 August 2016 | By Niamh Louise Marriott, Digital Content Producer
Foetal haemoglobin lacks beta sub-units and has gamma sub-units instead. Thus, beta-thalassemia or SCD–associated mutations, which impair the production or function of the beta sub-unit, do not cause problems with foetal haemoglobin, which can transport oxygen effectively in adults...
15 August 2016 | By Niamh Louise Marriott, Digital Content Producer
Targeting a single protein, SUPT4H1, reduces the levels of the three toxic entities created by the C9orf72 gene expansion, the most common genetic cause of ALS...
11 August 2016 | By University of Manchester
Transgenic mice that develop symptoms of Alzheimer's disease were used with one group of 10 treated with mefenamic acid, and 10 with a placebo. The mice were treated at a time when they had developed memory problems. After one month's treatment, memory loss was completely reversed back to the levels…
11 August 2016 | By Medical Research Council (MRC) Laboratory of Molecular Biology
HIV is surrounded by a protein shell called the capsid. It has now been found that HIV hides within the capsid while it builds DNA...
10 August 2016 | By Max Planck Institute for Heart and Lung Research
The most common cause of cancer deaths is not the primary tumour itself but metastases that subsequently form. Most tumour cells spread via the bloodstream. To do so, individual tumour cells have to enter blood vessels and leave the bloodstream again at remote locations...
10 August 2016 | By Niamh Louise Marriott, Digital Content Producer
The company 's intends to develop the most effective cannabis strains specific to pain, nausea, epilepsy and PTSD, solving the critical need for real science to support medical marijuana claims...
10 August 2016 | By Charles River Laboratories
Charles River Laboratories announced that it has entered into a strategic partnership with the Milner Therapeutics Institute and Consortium...
9 August 2016 | By Niamh Louise Marriott, Digital Content Producer
Three diseases; Chagas disease, leishmaniasis and sleeping sickness, all caused by parasites called ‘kinetoplastids, all sharing similar biology and genetics, leading scientists to investigate the possibility of a single chemical to destroy all three...
8 August 2016 | By Instituto Gulbenkian de Ciência
Researchers from the Instituto Gulbenkian de Ciência, Portugal, have discovered that the key controller of trunk, tail and spinal development is the Oct4 gene, one of the essential regulators of stem cells. The team intend to use their data to open new avenues to the study of spinal cord regeneration...
8 August 2016 | By St. Jude Children’s Research Hospital
Using vaccines prepared from killed viruses, the scientists targeted an influenza A H1N1 seasonal flu strain, finding that obese mice are not protected against influenza infections through vaccines, raising concerns about vaccine response in obese humans, who are known to be at an increased risk for severe flu...
5 August 2016 | By MDI Biological Laboratory
The ability of animals to regenerate body parts has always fascinated scientists but until the advent of sophisticated tools for genetic and computational analysis, they had no way of studying the genetic machinery that enables regeneration...
5 August 2016 | By Indiana University
Using rats carefully bred to either drink large amounts of alcohol or to spurn it, researchers at Indiana and Purdue universities have identified hundreds of genes that appear to play a role in increasing the desire to drink alcohol...
4 August 2016 | By Tokyo Institute of Technology
Certain species of amphibians and fish have the remarkable ability to regenerate tissue. Advances in molecular biological analyses have allowed researchers to identify specific molecules and signalling mechanisms involved in tissue regeneration. Fgf signalling is one such key mechanism...
4 August 2016 | By National Institute of Health (NIH)
Scientists have discovered 15 genome sites — the first ever — linked to depression in people of European ancestry. Many of these regions of depression-linked genetic variation turn out to be involved in regulating gene expression and the birth of new neurons in the developing brain...
