Human neurons in mouse brains are more susceptible to Alzheimer’s pathology
Cells behave differently when removed from their environments, just as cells that develop in cultures do not behave like cells in living creatures.
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How blood stem cells can be rejuvenated
Our blood stem cells generate around a thousand billion new blood cells every day. But the blood stem cells’ capacity to produce blood changes as we age. This leads to older people being more susceptible to anaemia, lowered immunity and a greater risk of developing certain kinds of blood cancer.
Obesity can reprogram muscle stem cells
Obesity is associated with reduced muscle mass and impaired metabolism. Epigenetic changes that affect the formation of new muscle cells may be a contributing factor, according to new research from Lund University, Sweden.
Deep Learning predicts hematopoietic stem cell development
Autonomous driving, automatic speech recognition, and the game Go: Deep Learning is generating more and more public awareness.
Stem cell ‘marking’ study offers alternative hypothesis of cancer metastasis
Stem cells are among the most energetically activated, migratory and proliferative sub-populations of tumour cells, according to observations by scholars at the Biomedical Research Centre at the University of Salford.
IT system failures in sample management
Successful compound management and biological sample management stand as key enablers within the drug discovery process...
New discovery to identify Huntington’s disease before symptoms appear
Early warning signs of Huntington’s disease have been uncovered in sheep carrying the human HD mutation, leading the way for new insight into this devastating illness, a new study has found.
Brain-machine interfaces: bidirectional communication at last
Since the early seventies, scientists have been developing brain-machine interfaces; the main application being the use of neural prosthesis in paralyzed patients or amputees. A prosthetic limb directly controlled by brain activity can partially recover the lost motor function. This is achieved by decoding neuronal activity recorded with electrodes and…
Pfizer Director of Biostatistics explores adaptive dose-finding designs in oncology early phase trials
Pfizer Director of Biostatistics to deliver key presentation at the 9th Adaptive Designs in Clinical Trials conference in London in April...
New tool developed to help avoid adverse drug reactions
Medicines are an important part of treating and preventing disease in adults and children. The ideal medicine would have no side effects or adverse drug reactions (ADRs) as they are also called, but the reality is all medicines can cause unwanted effects, in some people.
Significant epilepsy gene discovery in dogs
A collaborative study describes a novel myoclonic epilepsy syndrome in dogs for the first time and discovers its genetic cause at DIRAS1 gene.
Janssen and GSK provide keynote addresses at Controlled Release Delivery 2017
Returning to Central London for the 14th year, SMi’s Controlled Release Delivery conference will take place on the 3rd & 4th of April 2017...
Liverpool head and neck cancer research gets £200k boost
A research project, based out of the University of Liverpool, which will bring together a multidisciplinary team of cancer surgeons, medical oncologists and scientists in Liverpool, has been given the go ahead thanks to £200,000 worth of grant funding.
Cell death research shows promise for preventing Alzheimer’s
Alzheimer’s disease is a progressive neurodegenerative disorder that leads to dementia via advanced neuronal dysfunction and death. Currently, the predominant theory behind Alzheimer’s disease is the “amyloid hypothesis,” which states that abnormally increased levels of amyloid beta (Aβ) peptides outside of brain cells produce a variety of low molecular weight…
Mitochondrial lipids as potential targets for Parkinson’s disease
Using flies, mice and patient cells, the team focused on cardiolipin, a fat unique to cells’ mitochondria, organelles that produce energy.
