New insights into lung squamous cell carcinoma (LSCC) have emerged from a proteogenomic study, leading to the identification of potential drug targets.
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The RNA-modifying protein METTL1 could be targeted to treat some types of aggressive cancers, including brain, blood and kidney.
A US team has designed a high-quality, high-speed imaging system that could lead to new understandings of complex tissue specimens.
A screening method called dynamic BH3 profiling can identify potentially effective combinations of existing drugs for personalised cancer therapy, research has shown.
Researchers have shown antibodies induced by the Pfizer and Moderna vaccines are less effective at neutralising certain SARS-CoV-2 variants.
Researchers have developed a new tool that can add or remove sugar from proteins, which could be used to treat currently "undruggable" targets.
Dr Diogo Camacho from the Wyss Institute at Harvard discusses new research into using machine learning algorithms to analyse RNA sequences and reveal potential drug targets.
Researchers have found a way to systematically extract various cell types from induced pluripotent stem cells and made their transcription factor source accessible for other scientists.
Researchers from Massachusetts General Hospital have studied several thousand circulating proteins within the plasma proteome of symptomatic COVID-19 patients and acutely ill non-COVID-19 controls. Nikki Withers discussed their findings and implications of the study with one of the lead authors, Dr Mike Filbin.
The semi-automated process enabled researchers to make retinal organoid production and selection nearly four times faster.
A research team has developed a potentially universal flu vaccine that has demonstrated success in mice.
An analysis of SARS-CoV-2 has allowed researchers to identify epitopes recognised by a large fraction of COVID-19 patients, with 10 that could be targeted by antibodies.
A new technology named OligoFISSEQ has been created which can image and three-dimensionally map the genomes in hundreds of cells at the same time.
A new CRISPR technology has been created to understand mutations based on cytosine to guanine base changes and minimise unintended "off-target" mutations.
Drug Target Review lists its 10 most popular news stories from 2019, summarising the drug targets that you wanted to read about.