Using computational methods, researchers analysed the most popular CRISPR library designed for human cells and found 3,300 targeted spots that show strong toxic effects.
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Institute for Research in Biomedicine (IRB Barcelona)
The new study used cryo-electron microscopy to visualise the structure of a HAT protein and uncover compounds for drug development.
Using deep machine learning, researchers have completed the activity profiles, from chemistry to clinical level, for one million molecules.
Researchers show CDK8 inhibition reduces cell plasticity without damaging cells and suggest their approach could have implications for autoimmunity and oncology.
Computational analysis has been used by researchers to examine 66 types of cancer and identify 568 genes that drive tumour development.
A new study has identified possible regulators that determine differences in cancer tumours between genders.
A new study shows that the activity of p38 is important in MSCs, which can localise around blood vessels.
A study by researchers at the Institute for Research in Biomedicine has been the first to achieve stable simulations of DNA crystals...
A team of researchers led by IRB Barcelona in Spain have identified a key function of the enzyme EXD2 as being the maintenance of protein production in the mitochondria.
Scientists have made a significant breakthrough in understanding how the molecular machines that produce key proteins are cleaned and maintained. ..