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Documenting the mammalian brain using machine learning
Novel approaches to brain disorder diagnosis and treatment may be developed following a project to form a map of the mouse hippocampus.
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National Institutes of Health
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Extracellular vesicles could slow spread of fibrosis
US researchers studied the extracellular vesicles of fibrosis and find potential avenue for new treatments and therapeutics.
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A structural insight into HIV drug-resistance mechanisms
New Salk Institute, US, research could lead to the development of new HIV therapeutics that overcome resistance to existing drugs.
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Helper T cells may hold key to precision allergy treatment
US researchers have connected a rare T cell called Th9 with treating allergies, testing in mouse models with asthma.
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Study identifies key regulator of cell differentiation
Long-awaited findings about cell differentiation will be relevant in understanding normal development and may also be useful in cancer research.
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Cancer-promoting gene a potential target for pulmonary hypertension
The new study identified PDZ-binding kinase (PBK) as a promising target for pulmonary hypertension and assessed two PBK inhibitors.
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Antibody characterisation – an essential researchers’ resource
Central to reproducibility in biomedical research is the ability to use well-characterised and defined reagents. The CPTAC Antibody Portal serves as a National Cancer Institute community resource that provides access to many standardised renewable affinity reagents to cancer-associated targets and accompanying characterisation data. Nikki Withers spoke to Dr Tara Hiltke…
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New CRISPR technique could alter the way we look at brain diseases
Researchers may have fundamentally altered the way scientists study brain diseases with new CRISPR technology.
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New model can help translate mice research into human health results
A new mouse model, called 'wildlings', has been developed which better mirrors human immune responses than standard laboratory mice.
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Experimental treatment slows prion disease
A new experiment has not only slowed the progression of the prion disease, scrapie, it also extended the lives of prion-infected mice
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Scientists create map of brain region linked to Alzheimer’s disease
Scientists have mapped areas of the brain that are linked to Alzheimer's disease to deliver genetically-targeted drugs to specific neurons...
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New drug for ALS ready for clinical trials
Previous studies have suggested that a gene therapy drug may be used to treat ALS...
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IgM antibodies protect against HIV-1 infection
A group of scientists have zeroed in on a new defence against HIV-1, the virus that causes AIDS...
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SPECT Imaging technique illuminates immune status of monkeys with HIV-like virus
Approach could improve understanding of immune system recovery in people treated for HIV infection...
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Cellular barcoding helps scientists understand the behaviour of stem cells
Use of labelling technology in mice leads to discoveries in process of natural blood formation...