Altering the mastoparan-L (mast-L) peptide found in Vespula lewisii wasp venom, researchers created several novel antimicrobial molecules.
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Perelman School of Medicine at the University of Pennsylvania
The mechanism that prevents destruction of cancer cells by CAR T-cell therapy has been identified by researchers in Pennsylvania.
Almost all animal subjects exposed to genital herpes were protected by the novel vaccine.
Researchers have found that inhibiting a kinase in mice leads to the death of prostate cancer cells, providing a potential therapeutic target.
A study has revealed a drug target for skin cancers which regulates the differentiation of cells and the roles they conduct in the body.
PARP inhibitors show promise in preventing toxic accumulations of brain disease proteins in Penn research study...
A protein identified in the signalling pathway for haemoglobin production has been identified as a possible target to treat sickle cell disease (SCD)...
Reversing modifications in diseased heart muscle cell struts called microtubules (MT) can lessen the stiffness and improve the beating strength of these cells isolated from transplant patients with heart failure.
A new scientific statement summarises the state-of-the-science of genomic medicine...
Using data from multiple molecular databases, researchers from the University of Pennsylvania have found nine distinct types of exhausted T cells (‘Tex’), which could have implications for fighting chronic infections, autoimmunity, and cancer.
Researchers found that the type of brain cell afflicted in Parkinson’s-related brain disorders dictates which pathological form of α-synuclein (α-syn) protein becomes the disease culprit.
New findings have made inroads into a strategy to identify TNBC tumours at risk for metastasis...