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Faster drug discovery could hit ‘undruggable’ targets
A new technique has been developed which has the potential to harness bacteria to produce billions of different drug candidates to treat diseases like cancer.
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Michigan University
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Industry collaborate to screen existing drugs to repurpose for cystic fibrosis
In an effort to address some of the more serious untreatable infections encountered by patients with cystic fibrosis, Calibr will collaborate with the Cystic Fibrosis Foundation on a two-year project.
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Getting precise: how humanised models aid in biologics drug discovery
Humanised immune system (HIS) models have enabled numerous in vivo evaluations of immuno-modulating biologic drugs and ongoing improvements continue to extend their utility. Paul Volden explores the application of HIS models in precision and personalised medicine with a focus on biologics, including how HIS models are used, why they are…
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New technique enables detailed genetic analysis of cancer cells
A new way to cleanly separate out cancer cells from a blood sample will enable comprehensive genetic profiling of the cancer cells.
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New DNA ‘shredder’ technique goes beyond CRISPR’s scissors
A new CRISPR-based tool that acts more like a shredder is able to wipe out long stretches of DNA in human cells with programmable targeting...
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Non-invasive imaging for small airway lung disease
A non-invasive method of imaging tiny bronchioles in the lungs of chronic obstructive pulmonary disease means patients could detect the disease earlier...
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Live-imaging technique reveals cellular plug for leaky bio barrier
A microscopy assay has shown the repair mechanism involved in the activation of a protein called Rho, used to plug leaky biological barriers in the body...
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mEAK-7 gene could suggest path towards cancer therapies
Researchers have found mEAK-7 regulates the molecular process that dictates cell growth and human development...
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New study suggests possible marker to test patient immunotherapy benefit
While immunotherapy has made a big impact on cancer treatment, the fact remains that only about a quarter of patients respond to these treatments.
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CXCL5 protein found to stimulate tumour growth in prostate cancer
Researchers identify a pathway that causes tumour acceleration in metastatic prostate cancer cells...
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CYC065-eribulin combination therapy for triple-negative breast cancer identified
Researchers find novel combination disrupts multiple factors in aggressive breast cancer...
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Largest psoriasis meta-analysis to date yields new genetic clues
1-2% of the US population have psoriasis, an immune-mediated disease that causes red, patchy and scaly marks on the skin.
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Immunotherapy and gene therapy combination shows promise against brain tumours
The outlook for brain tumour patients is pretty negative, with the median survival rate for patients with glioblastoma multiforme, or GBM, a mere 14.2 months.
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BanLec: the banana-derived antiviral agent
23 October 2015 | By Victoria White
BanLec, a substance originally found in bananas and carefully edited by scientists, could someday fight off a wide range of viruses...
