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Possible target found for idiopathic pulmonary fibrosis treatment
A new study shows that using therapeutic antibodies to block the interleukin-11 protein can reverse idiopathic pulmonary fibrosis.
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New vaccine prevents genital herpes in mice and guinea pigs
Almost all animal subjects exposed to genital herpes were protected by the novel vaccine.
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Short peptides discovery could lead to new treatments for Alzheimer’s
The memory of mice with Alzheimer's greatly improved after they were injected with two newly discovered short peptides.
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Slowing progression in Parkinson’s
Currently, there is no licensed treatment to slow or stop the progression of Parkinson’s disease. However, a team at Sheffield University in the UK are currently working to identify compounds that target the dopaminergic brain cells affected by the disease. Nikki Withers speaks to Dr Heather Mortiboys to hear how…
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Recent trends in upstream bioprocessing and major challenges in process development
Aparajita Dubey summarises the recent trends in upstream bioprocessing and highlights the challenges and solutions involved in its process development.
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Researchers explain how lymphoma cells metastasise to the brain
Chronic inflammatory processes in ageing brains lead to lymphoma cells that have entered the brain tissue being retained.
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Role of gut microbiota studied in pregnant women with lupus
New research findings suggest that gut microbiota may regulate lupus flares in pregnant women, presenting a therapeutic target.
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New strategy developed to speed up drug discovery process
A new drug discovery strategy predicts the clinical actions of new compounds to promote desired clinical responses and avoid side effects.
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Expert view: Advancing antibody discovery with picodroplet technology
It is predicted that there will be 70 new monoclonal antibody (mAb) biotherapeutics available by 2020.
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New treatments for liver disease could be identified with lab-on-a-chip
New lab on a chip technology has been developed to evaluate the effects of different drivers of NAFLD on liver cells.
whitepaper
eBook: Explore cells from the inside out
Modern cell biology requires a wide variety of applications to keep up with the numerous exciting directions that research takes us. Detection technologies ranging from fluorescence to cellular imaging have become common in today’s laboratories.
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Succinate in cystic fibrosis lungs feeds deadly bacteria
Targeting a deadly bacteria's use of succinate in the lungs could control infection and improve the health of people with cystic fibrosis.
whitepaper
Flyer: Affinity Column for Fast Evaluation of ADCC Activity
TSKgel FcR-IIIA-NPR is based on a recombinant FcγIIIa receptor ligand immobilized on a non-porous polymer particle. It allows fast assessment of biologic activity of monoclonal antibodies.
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Cyclisation reaction enables screening of macrocyclic compounds libraries
Libraries of more than 9,000 macrocyclic molecules below 1 KDa have been generated, small enough to cross cell membranes and reach targets.
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Osteoporosis in mice reversed with new drug target
A pharmaceutical target has been identified by Duke University that, when activated, can reverse bone degradation caused by osteoporosis.
