Analysis

Expert view: Advancing antibody discovery with picodroplet technology

13 September 2019 | By Sphere Fluidics Ltd.

It is predicted that there will be 70 new monoclonal antibody (mAb) biotherapeutics available by 2020.

New treatments for liver disease could be identified with lab-on-a-chip

30 August 2019 | By Rachael Harper (Drug Target Review)

New lab on a chip technology has been developed to evaluate the effects of different drivers of NAFLD on liver cells.

eBook: Explore cells from the inside out

23 August 2019 | By Molecular Devices

Modern cell biology requires a wide variety of applications to keep up with the numerous exciting directions that research takes us. Detection technologies ranging from fluorescence to cellular imaging have become common in today’s laboratories.

Succinate in cystic fibrosis lungs feeds deadly bacteria

23 August 2019 | By Rachael Harper (Drug Target Review)

Targeting a deadly bacteria's use of succinate in the lungs could control infection and improve the health of people with cystic fibrosis.

Flyer: Affinity Column for Fast Evaluation of ADCC Activity

22 August 2019 | By Tosoh

TSKgel FcR-IIIA-NPR is based on a recombinant FcγIIIa receptor ligand immobilized on a non-porous polymer particle. It allows fast assessment of biologic activity of monoclonal antibodies.

Cyclisation reaction enables screening of macrocyclic compounds libraries

22 August 2019 | By Rachael Harper (Drug Target Review)

Libraries of more than 9,000 macrocyclic molecules below 1 KDa have been generated, small enough to cross cell membranes and reach targets.

Osteoporosis in mice reversed with new drug target

21 August 2019 | By Rachael Harper (Drug Target Review)

A pharmaceutical target has been identified by Duke University that, when activated, can reverse bone degradation caused by osteoporosis.

New drug target for glioblastoma identified by study

21 August 2019 | By Rachael Harper (Drug Target Review)

A new drug target for treating glioblastoma has been identified from a cellular pathway found to contribute to the spread of glioma stem cells.

Tosoh Bioscience

New study reveals causes of stem cell transplant rejection

20 August 2019 | By Rachael Harper (Drug Target Review)

A new study has shown that mutations in mitochondrial DNA induced by cell reprogramming may trigger an immune response.

Optofluidic chip platform developed for single molecule analysis

19 August 2019 | By Rachael Harper (Drug Target Review)

A new platform has enabled an unprecedented level of control over individual molecules and particles on a chip for high-throughput analysis.

Genes responsible for gender differences in tumours identified

19 August 2019 | By Rachael Harper (Drug Target Review)

A new study has identified possible regulators that determine differences in cancer tumours between genders.

Genes linked to Alzheimer’s risk have been identified

15 August 2019 | By Nic Losardo (Drug Target Review)

Two genes that influence risk Alzheimer's disease could provide scientists with new targets for delaying the onset of the condition's symptoms.

Blood-brain barrier role in Alzheimer’s patients revealed by tissue model

13 August 2019 | By Rachael Harper (Drug Target Review)

A new study has found that damage caused by Alzheimer's allows toxins to enter the brain, further harming neurons.

Therapeutic target for Kennedy’s disease and prostate cancer proposed

9 August 2019 | By Rachael Harper (Drug Target Review)

A chaperone protein has been identified as a possible therapeutic target for the treatment of Kennedy's disease and prostate cancer.